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SIRT6 recruits SNF2H to sites of DNA breaks, preventing genomic instability through chromatin remodeling
(Cell Press, 2013-08)
DNA damage is linked to multiple human diseases, such as cancer, neurodegeneration, and aging. Little is known about the role of chromatin accessibility in DNA repair. Here, we find that the deacetylase sirtuin 6 (SIRT6) ...
Hexavalent chromium removal in contaminated water using reticulated chitosan micro/nanoparticles from seafood processing wastes
(Elsevier, 2015-07)
Chitosan particles (CH) were obtained from seafood processing wastes (shrimp shells) and physicochemically characterized; deacetylation degree of CH was measured by Infrared Spectroscopy (FTIR) and potentiometric titration; ...
Pattern of alkali impregnation of poplar wood at moderate conditions
(De Gruyter, 2000-10)
The impregnation pattern of alkali in fresh Cottonwood is analysed. Isothermal process, medium alkali-concentration, temperature below 100°C and tangential direction are considered. The degree of deacetylation in the wood ...
Preliminary study on the use of chitosan as an eco-friendly alternative to control fusarium growth and mycotoxin production on maize and wheat
(MDPI AG, 2019-03)
The objectives of the present study were to determine the combined effects of chitosan and water activity (a W ) on growth and mycotoxin production in situ on the two most important Fusarium species (F. proliferatum and ...
Honokiol attenuates oxidative stress-dependent heart dysfunction in chronic Chagas disease by targeting AMPK / NFE2L2 / SIRT3 signaling pathway
(Elsevier Science Inc., 2020-08)
Chronic cardiomyopathyis the most serious and frequent manifestation of Chagas disease caused by Trypanosoma cruzi. Free radicals are acrucial factor in Chagas pathogenesis. Parasite infection of cardiomyocytesexacerbates ...
Pre-exposure to nicotine with nocturnal abstinence induces epigenetic changes that potentiate nicotine preference
(Humana Press, 2019-12)
Prior exposure to drugs of abuse may facilitate addiction. It has been described that pre-exposure to nicotine can increase or, contrarily, prevent conditioned place preference (CPP). Here, we evaluated the effect of ...
Fetal metabolic programming and epigenetic modifications: a systems biology approach
(Nature Publishing Group, 2013-04)
A growing body of evidence supports the notion that epigenetic changes such as DNA methylation and histone modifications, both involving chromatin remodeling, contribute to fetal metabolic programming. We use a combination ...
Salicylic acid loaded chitosan microparticles applied to lettuce seedlings: Recycling shrimp fishing industry waste
(Elsevier, 2018-11-15)
Shrimp fishing industry wastes are still a main problem with high environmental impact worldwide. In this study, chitosan with ultra-high molecular weight and deacetylation degree ≥85% was obtained from shrimp fishing ...
Food Biopackaging Based on Chitosan
(Springer, 2018)
Chitin, available from waste products of the shellfish industry (shells of the crab, shrimp, etc), is one of the most abundant natural polymers in world and it is used for the production of chitosan by deacetylation. Chitosan, ...
P66Shc Inactivation modifies RNS production, regulates Sirt3 activity, and improves mitochondrial homeostasis, delaying the aging process in mouse brain
(Landes Bioscience, 2018-03)
Programmed and damage aging theories have traditionally been conceived as stand-alone schools of thought. However, the p66Shc adaptor protein has demonstrated that aging-regulating genes and reactive oxygen species (ROS) ...