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Differential composition of culture supernatants from wild-type Brucella abortus and its isogenic virB mutants
(Springer, 2009-07)
The virB genes coding type IV secretion system are necessary for the intracellular survival and replication of Brucella spp. In this study, extracellular proteins from B. abortus 2308 (wild type, WT) and its isogenic virB10 ...
Biochemical characterization and cytotoxic effect of the skin secretion from the red-spotted Argentina frog Argenteohyla siemersi (Anura: Hylidae)
(Cevap-unesp, 2020-03)
Background: Argenteohyla siemersi (red-spotted Argentina frog) is a casque-headed tree frog species belonging to the Hylidae family. This species has a complex combination of anti-predator defense mechanisms that include ...
The hypophysis and secretion of insulin
(The Rockefeller University Press, 1942-01-05)
The action of the hypophysis on the pancreas has been demonstrated by a number of direct and indirect proofs. The latter, first reported from this Institute, are as follows: (a) Complete kypophysectomy or anterior (distal) ...
Identification of a type IV secretion substrate of Brucella abortus that participates in the early stages of intracellular survival
(Wiley Blackwell Publishing, Inc, 2014-03)
Brucella abortus, the aetiological agent of bovine brucellosis, is an intracellular pathogen whose virulence is completely dependent on a type IV secretion system. This secretion system translocates effector proteins into ...
Novel Effector Protein EspY3 of Type III Secretion System from Enterohemorrhagic Escherichia coli Is Localized in Actin Pedestals
(MDPI AG, 2018)
Enterohemorrhagic Escherichia coli (EHEC) and enteropathogenic Escherichia coli (EPEC) are attaching and effacing (A/E) pathogens, which translocate effector proteins to intestinal enterocytes through a type III secretion ...
HrpE, the major component of the Xanthomonas type three protein secretion pilus, elicits plant immunity responses
(Nature Publishing Group, 2018-12)
Like several pathogenic bacteria, Xanthomonas infect host plants through the secretion of effector proteins by the Hrp pilus of the Type Three Protein Secretion System (T3SS). HrpE protein was identified as the major ...
Evidence for constitutive bone morphogenetic protein-2 secretion by M1 macrophages: Constitutive auto/paracrine osteogenic signaling by BMP-2 in M1 macrophages
(Academic Press Inc Elsevier Science, 2017-09)
Mechanisms mediating vascular calcification recapitulate osteogenic processes encompassing bone formation and imply participation of bone related proteins such as bone morphogenetic protein-2 (BMP-2). Macrophages are amongst ...
Optimization of recombinant Zika virus NS1 protein secretion from HEK293 cells
(Elsevier, 2020-03)
Sensitive, accurate and cost-effective diagnostic tests are urgently needed to detect Zika virus (ZIKV) infection. Nonstructural 1 (NS1) glycoprotein is an excellent diagnostic marker since it is released in a hexameric ...
The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling
(Public Library of Science, 2014-03)
Chlamydia trachomatis, the causative agent of trachoma and sexually transmitted infections, employs a type III secretion (T3S) system to deliver effector proteins into host epithelial cells to establish a replicative ...
Biliary secretion and hepatic oxidative stress in animals fed with linoleic acid conjugates (CLA)
(Sociedad Argentina de Nutrición, 2008-12)
The purpose of this work was to investigate the effects of CLA at two levels (7 and 20%) of dietary fat on biliary secretion and oxidative stress in liver of rats. Animals were divided in four groups and fed with diets, ...