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Mycobacterium tuberculosis triggers apoptosis in peripheral neutrophils involving Toll-like receptor 2 and p38 mitogen protein kinase in tuberculosis patients
(American Society for Microbiology, 2004-09)
Polymorphonuclear neutrophils (PMN) exposed to Mycobacterium tuberculosis display bactericidal responses and produce inflammatory proteins. This PMN-mediated inflammatory response is regulated by an activation of the ...
Leptin stimulates protein synthesis-activating translation machinery in human trophoblastic cells
(Society for the Study of Reproduction, 2009-06)
Leptin was originally considered as an adipocyte-derived signaling molecule for the central control of metabolism. However, pleiotropic effects of leptin have been identified in reproduction and pregnancy, particularly in ...
Integrative study of hypothalamus-pituitary-thyroid-immune system interaction. Thyroid hormone mediated-modulation of lymphocyte activity through protein kinase C signaling pathway
(BioScientifica, 2006-01)
Thyroid hormones play critical roles in differentiation, growth and metabolism, but their participation in immune system regulation has not been completely elucidated. Modulation of in vivo thyroid status was used to carry ...
Docosahexaenoic acid prevents apoptosis of retina photoreceptors by activating the ERK/MAPK pathway
(Wiley Blackwell Publishing, Inc, 2006-07-26)
Identifying the trophic factors for retina photoreceptors and the intracellular pathways activated to promote cell survival is crucial for treating retina neurodegenerative diseases. Docosahexaenoic acid (DHA), the major ...
Differential Modulation of MAP Kinases by Zinc Deficiency in IMR-32 Cells: Role of H2O2.
(Mary Ann Liebert, 2005-11)
The influence of zinc deficiency on the modulation of the mitogen-activated protein kinases (MAPKs) extracellular signal-regulated kinase (ERK1/2), p38, and c-Jun N-terminal kinase (JNK) was studied. Using human IMR-32 ...
MAP kinases in proliferating human colon cancer Caco-2-cells
(Springer, 2009)
Involvement of PI3-kinase and its association with c-Src in PTH-stimulated rat enterocytes
(Wiley-liss, Div John Wiley & Sons Inc, 2002-06)
Phosphoinositide-3-kinase (PI3K) is a lipid kinase, which phosphorylates the D3 position of phosphoinositides, and is known to be activated by a host of protein tyrosine kinases. PI3K plays an important role in mitogenesis ...
Angiotensin II-upregulated MAP kinase phosphatase-3 modulates FOXO1 and p21 in adrenocortical H295R cells
(Cell Press, 2020-03)
MAPK phosphatases (MKP) downregulate the activity of mitogen-activated protein kinases (MAPK), such asERK1/2, and modulate the processes regulated by these kinases. ERK1/2 participate in a wide range of processesincluding ...
Role of PTHrP in human intestinal Caco-2 cell response to oxidative stress
(Elsevier, 2013-07)
We have previously demonstrated that parathyroid hormone (PTH) induces apoptosis in human colon adenocarcinoma Caco-2 cells but the effects of its tumoral analog PTH-related peptide (PTHrP) in this cell line are still ...
Efecto de la adición ex vivo del lipopolisacárido de E. Coli sobre la absorción de lisina en cerdos destete.Efecto de la adición de lipopolisacárido de escherichia coli ex vivo sobre la absorción de lisina en cerdos destetados
(Universidad Nacional de Colombia, Facultad de Ciencias AgrariasGrupo Interdisciplinario de Estudios MolecularesMedellín, Colombia, 2022)