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Electrochemical sensor for alkaline phosphatase as biomarker for clinical and in vitro applications
(Elsevier Science SA, 2019-02)
Alkaline phosphatase (ALP) is an important biomarker of bone diseases clinically measured in blood as a routine assay by means of optical read-outs, which when compared with electroanalytical methods present lack of ...
Increased calcium uptake and improved trabecular bone properties in intestinal alkaline phosphatase knockout mice
(Springer Tokyo, 2017-12)
Previous studies have demonstrated a negative correlation between intestinal alkaline phosphatase (IAP) activity and calcium (Ca) absorption in the gut, as IAP acts as a protective mechanism inhibiting high Ca entry into ...
Exploration of carboxy pyrazole derivatives: Synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase inhibition studies with potential anticancer profile
(Elsevier France-editions Scientifiques Medicales Elsevier, 2018-08)
In the present work we report the synthesis of new aryl pyrazole derivatives using 1,3-dicarbonyl motifs. The reaction was proceeded by the cyclization of pentane-2,4-dione (1a), 3-chloropentane-2,4-dione (1b) or ethyl ...
Fungal extracellular phosphatases: their role in P cycling under different pH and P sources availability
(Wiley Blackwell Publishing, Inc, 2018-01)
Aims: The aim of this work is to analyse the effect of pH, fungal identity and P chemical nature on microbial development and phosphatase release, discussing solubilization and mineralization processes in P cycling. Methods ...
Ejaculation training, seminal alkaline phosphatase and semen preservation through cooling in a milk-based extender in domestic cats
(Elsevier, 2014-06)
The purpose of this report is to describe (1) the training of domestic cats in ejaculation into an artificial vagina (AV), (2) alkaline phosphatase (AP) concentrations in whole ejaculates, and (3) the in vitro effect of a ...
Microfluidic immunosensor design for the quantification of interleukin-6 in human serum samples
(Academic Press Inc Elsevier Science, 2008-09)
Interleukin-6 (IL-6), an inflammatory cytokine, is one of the most important mediators of fever, the acute phase response, and inflammatory conditions. Described here is an integrated microfluidic immunosensor capable of ...
Computational study on the role of residue Arg166 in alkaline phosphatases
(Arkat USA, 2017-11)
Quantum chemical calculations were performed with the goal of achieving a better understanding of the influence of Arg166 on the catalytic activity of alkaline phosphatases. The present results indicate that the active ...
Turbidity and dissolved organic matter as significant predictors of spatio-temporal dynamics of phosphorus in a large river-floodplain system
(John Wiley & Sons Ltd, 2018-09)
Phosphorus (P) inputs are increasing in river‐floodplain systems, but the factors whichinfluence the dynamics of this nutrient are not clear. To assess P dynamics in this kindof river, the main channel of the Middle Paraná ...
Raphidiopsis mediterranea (Nostocales) exhibits a flexible growth strategy under light and nutrient fluctuations in contrast to Planktothrix agardhii (Oscillatoriales)
(Springer, 2019-06)
Raphidiopsis mediterranea is a freshwater cyanobacterium that forms toxic blooms in eutrophic water bodies. Factors controlling its proliferation have not been explored in detail. We investigated R. mediterranea autecology ...