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Metabolite Signatures of Metabolic Risk Factors and their Longitudinal Changes
(Endocrine Society, 2016-04)
CONTEXT: Metabolic dysregulation underlies key metabolic risk factors—obesity, dyslipidemia, and dysglycemia.
OBJECTIVE: To uncover mechanistic links between metabolomic dysregulation and metabolic risk by testing metabolite ...
Association of common variants in JAK2 gene with reduced risk of Metabolic Syndrome and related disorders
(BioMed Central, 2011-11)
Background: Disturbances in leptin and insulin signaling pathways are related to obesity and metabolic syndrome (MS) with increased risk of diabetes and cardiovascular disease. Janus kinase 2 (JAK2) is a tyrosine kinase ...
Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome
(Molecular Diversity Preservation International, 2020-10)
Metabolic Syndrome (MetS) is increasing worldwide regardless of culture, genetic, gender, and geographic differences. While multiple individual risk factors, such as obesity, hypertension, diabetes, and hyperlipidemia, can ...
Biochemical study of idebenone effect on mitochondrial metabolism of yeast
(Academic Press Ltd - Elsevier Science Ltd, 2008-12)
The aim of this work was to study the effect of the drug idebenone on the growth of a strain of Saccharomyces cerevisiae yeast and its respiratory-deficient mutant (rho0). We took this yeast as a model system of the ...
FABP1 knockdown in human enterocytes impairs proliferation and alters lipid metabolism
(Elsevier Science, 2017-12)
Fatty Acid-Binding Proteins (FABPs) are abundant intracellular proteins that bind long chain fatty acids (FA) and have been related with inmunometabolic diseases. Intestinal epithelial cells express two isoforms of FABPs: ...
Lipid accumulation product: a powerful marker of metabolic syndrome in healthy population
(BioScientifica, 2011-04)
Objective: The metabolic syndrome (MS) is a cluster of cardiometabolic factors which predisposes to diabetes and cardiovascular disease (CVD). Early detection of high-risk individuals for MS using accurate measures of ...
BEHAVIOR OF HEALTH INDICATORS OF RURAL WORKERS AFTER HEALTH EDUCATION ACTIONS
(Universidade Federal de Santa Maria, 2022)
Presenting signs and patient co-variables in Gaucher disease: outcome of the Gaucher Earlier Diagnosis Consensus (GED-C) Delphi initiative
(Wiley Blackwell Publishing, Inc, 2019-05)
Background: Gaucher disease (GD) presents with a range of signs and symptoms. Physicians can fail to recognise the early stages of GD owing to a lack of disease awareness, which can lead to significant diagnostic delays ...