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Galectin‐8 activates dendritic cells and stimulates antigen‐specific immune response elicitation
(2017-11)
Galectin‐8 (Gal‐8) is a mammalian β‐galactoside‐binding lectin, endowed with proinflammatory properties. Given its capacity to enhance antigen‐specific immune responses in vivo, we investigated whether Gal‐8 was also able ...
Combining inhibition of galectin-3 with and before a therapeutic vaccination is critical for the prostate-Tumor-free outcome
(BMJ Publishing Group, 2020-12)
Background Prostate cancer (PCa) is a major health problem worldwide. Taxol derivatives-based chemotherapies or immunotherapies are usually proposed depending on the symptomatic status of the patient. In the case of ...
Control of intestinal inflammation by glycosylation-dependent lectin-driven immunoregulatory circuits
(Science Advances is the American Association for the Advancement of Science, 2021-06)
Diverse immunoregulatory circuits operate to preserve intestinal homeostasis and prevent inflammation. Galectin-1 (Gal1), a β-galactoside-binding protein, promotes homeostasis by reprogramming innate and adaptive immunity. ...
Characterization and functionality of proliferative human sertoli cells
(Cognizant Communication Corp, 2011-05)
It has long been thought that mammalian Sertoli cells are terminally differentiated and nondividing postpuberty. For most previous in vitro studies immature rodent testes have been the source of Sertoli cells and these ...
Interfering with Gal-1–mediated angiogenesis contributes to the pathogenesis of preeclampsia
(National Academy of Sciences, 2013)
Galectin-3 controls the response of microglial cells to limit cuprizone-induced demyelination
(Elsevier, 2014-02)
Galectin-3 (Gal-3) is a β-galactoside-binding lectin that plays an important role in inflammatory and neurodegenerative diseases. Cuprizone (CPZ)-induced demyelination is characterized by the loss of mature oligodendrocytes ...