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BPAN manifesting with febrile seizures and language delay:a case report from Brazil
(HCPA/FAMED/UFRGS, 2021)
Calcium and Magnesium Urinary Excretion in Dairy Cows with Different Fee of Glucose Metabolization
(Universidade Federal do Rio Grande do Sul, 2018)
Mulinum spinosum root extract, rich in antioxidant compounds, mitigates harmful effects in mice with diet-induced metabolic syndrome
(Elsevier, 2022-02)
Background: Metabolic syndrome (MetS) is a health issue with a high incidence in adult population. Using herbal medicines for the management of serious complications of MetS, such as dyslipidemia and hyperglycemia, is ...
Aspartate transport and metabolism in the protozoan parasite Trypanosoma cruzi
(Wiley Blackwell Publishing, Inc, 2005-06)
Aspartate is one of the compounds that induce the differentiation process of the non-infective epimastigote stage to the infective trypomastigote stage of the protozoan parasite Trypanosoma cruzi. l-aspartate is transported ...
Poly(ADP-ribose) metabolism in human parasitic protozoa
(Elsevier Science, 2020-08-22)
Poly(ADP-ribosyl)ation reactions constitute a post-translational protein modification synthesized in higher eukaryotes by a family of poly(ADP-ribose)polymerases (PARP) and catabolized mainly by poly(ADP-ribose) glycohydrolase ...
Targeting defective sphingosine kinase 1 in Niemann–Pick type C disease with an activator mitigates cholesterol accumulation
(American Society for Biochemistry and Molecular Biology, 2020-07)
Niemann–Pick type C (NPC) disease is a lysosomal storage disorder arising from mutations in the cholesterol-trafficking protein NPC1 (95%) or NPC2 (5%). These mutations result in accumulation of low-density lipoprotein-derived ...
CLCA2 epigenetic regulation by CTBP1, HDACs, ZEB1, EP300 and miR-196b-5p impacts prostate cancer cell adhesion and EMT in metabolic syndrome disease
(John Wiley & Sons Inc, 2018-08)
Prostate cancer (PCa) is the most common cancer among men. Metabolic syndrome (MeS) is associated with increased PCa aggressiveness and recurrence. Previously, we proposed C-terminal binding protein 1 (CTBP1), a transcriptional ...
Neuroinflammation and aging: focus on experimental Alzheimer´s disease
(Pan American Neuroendocrine Society, 2019)
The incidence of metabolic disorders including obesity, diabetes and metabolic syndrome have seriously increased in the last decades. These diseases - with growing impact in modern societies - constitute major risk factors ...