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Characterization of folding-sensitive nanobodies as tools to study the expression and quality of protein particle immunogens
(Elsevier Science, 2019-03)
Vaccination is as one of the most beneficial biopharmaceutical interventions against pathogens due to its ability to induce adaptive immunity through targeted activation of the immune system. Each vaccine needs a tailor-made ...
Forkhead box O1 (FOXO1) protein, but not p53, contributes to robust induction of p21 expression in fasted mice
(American Society for Biochemistry and Molecular Biology, 2013-09)
Reporter mice that enable the activity of the endogenous p21 promoter to be dynamically monitored in real time in vivo and under a variety of experimental conditions revealed ubiquitous p21 expression in mouse organs ...
Time-dependent sequestration of RVE8 by LNK proteins shapes the diurnal oscillation of anthocyanin biosynthesis
(National Academy Of Sciences, 2015-04)
Circadian clocks sustain 24-h rhythms in physiology and metabolism that are synchronized with the day/night cycle. In plants, the regulatory network responsible for the generation of rhythms has been broadly investigated ...
Transformation of Solanum tuberosum plastids allows high expression levels of β-glucuronidase both in leaves and microtubers developed in vitro
(Springer, 2012-04)
Plastid genome transformation offers an attractive methodology for transgene expression in plants, but for potato, only expression of gfp transgene (besides the selective gene aadA) has been published. We report here ...
Protein and gene expression of relevant enzymes and nuclear receptor of hepatic lipid metabolism in grazing dairy cattle during the transition period
(Elsevier, 2019-04)
We aimed to study the protein and gene expression of some hepatic enzymes of lipid metabolism along with plasma biomarkers in grazing dairy cattle during the transition period. Blood and liver biopsies from a group of eight ...
Heat shock proteins are essential components in transformation and tumor progression: Cancer cell intrinsic pathways and beyond
(Institute for Digital Multidisciplinary Publication, 2019-09)
Heat shock protein (HSP) synthesis is switched on in a remarkably wide range of tumor cells, in both experimental animal systems and in human cancer, in which these proteins accumulate in high levels. In each case, elevated ...
Recombinant canarypox virus expressing the VP2 protein of infectious bursal disease virus induces protection in vaccinated SPF chickens
(Springer, 2016-03)
Infectious bursal disease virus (IBDV) is the causative agent of an immunosuppressive disease that causes important economic losses to the poultry industry. Current attenuated viral vaccines pose drawbacks and risks and ...
Las bacterias como sistema de expresión de proteínas heterólogas terapéuticas : una revisión bibliográficaBacteria as a therapeutic heterologous protein expression system: a review
(Universidad de Antioquia, Escuela de MicrobiologíaMedellín, Colombia, 2019)
Production of recombinant NS1 protein and its possible use in encephalitic flavivirus differential diagnosis
(Elsevier Inc, 2019-08-17)
Saint Louis encephalitis virus (SLEV) and West Nile virus (WNV) are two of the major causes of arboviral encephalitis in the Americas. The co-circulation of related flaviviruses in the Americas and prior vaccination against ...