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DNA related enzymes as molecular targets for antiviral and antitumoral chemotherapy. A natural overview of the current perspectives
(Bentham Science Publishers, 2019-01)
Background: The discovery of new chemotherapeutic agents still remains a continuous goal to achieve. DNA polymerases and topoisomerases act in nucleic acids metabolism modulating different processes like replication, ...
Proteome variation of the rat liver after static cold storage assayed in an ex vivo model
(Academic Press Inc Elsevier Science, 2018-12)
Cold storage is a common procedure for liver preservation in a transplant setting. However, during cold ischemia, the liver suffers molecular alterations that can affect its performance. Also, deleterious mechanisms set ...
Out of sight, out of mind: Phylogenetic and taxonomic gaps imply great underestimations of the species’ vulnerability to global climate change
(Associacao Brasileira de Ciencia Ecologica e Conservacao, 2021-04)
The study of the species’ climatic niche is an excellent proxy of their vulnerability to global climate change. It is well known that species with greater niche marginality or a smaller niche breadth are most vulnerable ...
Reflexiones ideológicas sobre ideologíaIdeological reflections about ideology
(Universidad de Buenos Aires. Facultad de Ciencias Sociales. Instituto de Investigaciones Gino Germani, 2021-12)
En este artículo se recorren distintas aproximaciones al concepto de ideología, resaltando que todas y cada una de ellas no dejan, por su parte, de ser igualmente ideológicas. Esto no supone un desvalor, por cuanto no ...
Potential use of Citrus essential oils against acute respiratory syndrome caused by coronavirus
(Allured Publishing Corporation, 2021-04-19)
The treatments being investigated for the pandemic associated with a severe acute respiratory syndrome caused by the new coronavirus (SARS-CoV2) aim to inhibit viral replication or inhibit enzymatic elastase in the lung, ...
Prenatal ethanol exposure increases ethanol intake and reduces C-fos expression in infralimbic cortex of adolescent rats
(Elsevier Inc, 2012-12)
Prenatal ethanol exposure significantly increases later predisposition for alcohol intake, but the mechanisms associated with this phenomenon remain hypothetical. This study analyzed (Experiment 1) ethanol intake in ...
Naturally Derived Heme-Oxygenase 1 Inducers and Their Therapeutic Application to Immune-Mediated Diseases
(Frontiers Media S.A., 2020-07)
Heme oxygenase (HO) is the primary antioxidant enzyme involved in heme group degradation. A variety of stimuli triggers the expression of the inducible HO-1 isoform, which is modulated by its substrate and cellular stressors. ...
La elaboración de identidades mundializadas a través del trap: Marginalidades juveniles, consumismo y experimentación musicalConstruction of globalized identities through trap: Youth marginalities, consumerism and musical experimentation
(Instituto Nacional de Musicología Carlos Vega, 2018-12)
El trap es una música electrónica que se ha difundido con rapidez a través de internet. Productores, artistas y público forman parte, por lo general, de distintas marginalidades juveniles que encuentran puntos de contacto ...
Purification and characterization of a novel trypsin inhibitor from Solanum tuberosum subsp. andigenum var. overa: Study of the expression levels and preliminary evaluation of its antimicrobial activity
(Elsevier Science, 2020-09-01)
Protease inhibitors (PIs) have been traditionally recognized by their potential biomedical application in events with exacerbation of endogenous proteases activity. Plant PIs have gained interest as naturally occurring ...
Additive negative effects of Philornis nest parasitism on small and declining Neotropical bird populations
(Elsevier, 2018-09)
The declining-population paradigm holds that small populations are particularly vulnerable to anthropogenic influences such as habitat destruction, pollution and species introductions. While the effects of particular ...