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Environmental concentrations of azinphos-methyl cause different toxic effects without affecting the main target (cholinesterases) in the freshwater gastropod Biomphalaria straminea
(Academic Press Inc Elsevier Science, 2018-10)
Organophosphate insecticides (OPs) are commonly used in Argentina and around the world for pest control in food crops. They exert their toxicity through the inhibition of the enzyme acetylcholinesterase. In the present ...
The ADP-glucose pyrophosphorylase from Streptococcus mutans provides evidence for the regulation of polysaccharide biosynthesis in Firmicutes
(Wiley, 2013-10)
Streptococcus mutans is the leading cause of dental caries worldwide. The bacterium accumulates a glycogen-like internal polysaccharide, which mainly contributes to its carionegic capacity. S. mutans has two genes (glgC ...
Nitrification and aerobic denitrification in anoxic-aerobic sequencing batch reactor
(Elsevier, 2016-01)
The aim of this study was to evaluate the feasibility of achieving nitrogen (N) removal using a lab-scale sequencing batch reactor (SBR) exposed to anoxic/aerobic (AN/OX) phases, focusing to achieve aerobic denitrification. ...
Mechanisms of monomeric and dimeric glycogenin autoglucosylation
(American Society for Biochemistry and Molecular Biology, 2012-01)
Initiation of glucose polymerization by glycogenin autoglucosylation at Tyr-194 is required to prime de novo biosynthesis of glycogen. It has been proposed that the synthesis of the primer proceeds by intersubunit glucosylation ...
Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels
(Society for Neuroscience, 2014-12-03)
Neurons use glucose to fuel glycolysis and provide substrates for mitochondrial respiration, but neurons can also use alternative fuels that bypass glycolysis and feed directly into mitochondria. To determine whether ...
Ultrasensitive behavior in the synthesis of storage polysaccharides in cyanobacteria
(Springer Heidelberg, 2003-04)
The glycogen synthetic pathway operates ultrasensitively as a function of the ADPglucose pyrophosphorylase (ADPGlcPPase) allosteric effectors, 3-phosphoglycerate and Pi, in permeabilized cells of the cyanobacterium Anabaena ...
The euryhaline crab Uca tangeri showed metabolic differences to sex and environmental salinity
(Cambridge University Press, 2018-09-03)
This study constitutes a first attempt to investigate sex differences in osmoregulatory capacity and metabolic responses in relation to hyper-and hypo-osmoregulation in the intertidal euryhaline crab Uca tangeri. Adult ...
Identification of regions critically affecting kinetics and allosteric regulation of the Escherichia coli ADP-glucose pyrophosphorylase by modeling and pentapeptide-scanning mutagenesis
(American Society for Microbiology, 2007-07)
ADP-glucose pyrophosphorylase (ADP-Glc PPase) is the enzyme responsible for the regulation of bacterial glycogen synthesis. To perform a structure-function relationship study of the Escherichia coli ADP-Glc PPase enzyme, ...
Effects of the AMP-activated protein kinase inhibitor compound C on the postconditioned rat heart
(Springer Tokyo, 2012-07)
Ischemic postconditioning (IPOC) protects the myocardium from ischemic-reperfusion injury, improving functional recovery and cell viability. This protection is concurrent with stimulation of glycogen breakdown, increased ...