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Nitric oxide synthase I and VIP-activated signaling are affected in salivary glands of NOD mice
(Elsevier Science, 2002-06)
The autoimmune sialadenitis developed by non-obese diabetic (NOD) mice is considered a suitable model to study the ethiopathogenic mechanisms leading to sicca symptoms in Sjo¨gren’s syndrome (SS). Evidence supporting a ...
Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations
(Public Library of Science, 2017-06)
Ultrasensitive response motifs, capable of converting graded stimuli into binary responses, are well-conserved in signal transduction networks. Although it has been shown that a cascade arrangement of multiple ultrasensitive ...
Ubiquitin-proteasome signaling in lung injury
(Elsevier Science Inc., 2018-08)
Cell homeostasis requires precise coordination of cellular proteins function. Ubiquitination is a post-translational modification that modulates protein half-life and function and is tightly regulated by ubiquitin E3 ligases ...
Synthesis of multiport resistors with piecewise-linear characteristics: a mixed-signal architecture
(John Wiley & Sons Ltd, 2005-07)
Non‐linear multiport resistors are the main ingredients in the synthesis of non‐linear circuits. Recently, a particular PWL representation has been proposed as a generic design platform (IEEE Trans. Circuits Syst.‐I 2002; ...
Auxin signaling participates in the adaptative response against oxidative stress and salinity by interacting with redox metabolism in Arabidopsis
(Springer, 2010-07)
Auxin regulates gene expression through direct physical interaction with TIR1/AFB receptor proteins during different processes of growth and development in plants. Here we report the contribution of auxin signaling pathway ...
Seed transcriptome annotation reveals enhanced expression of genes related to ros homeostasis and ethylene metabolism at alternating temperatures in wild cardoon
(MDPI AG, 2020-09)
The association among environmental cues, ethylene response, ABA signaling, and reactive oxygen species (ROS) homeostasis in the process of seed dormancy release is nowadays well-established in many species. Alternating ...
CFTR modulates RPS27 gene expression using chloride anion as signaling effector
(Elsevier Science Inc, 2017-09)
In Cystic Fibrosis (CF), the impairment of the CFTR channel activity leads to a variety of alterations, including differential gene expression. However, the CFTR signaling mechanisms remain unclear. Recently, culturing ...
Changes in Ca2+ removal can mask the effects of geometry during IP3R mediated Ca2+ signals
(Frontiers Media, 2019-07-31)
Calcium (Ca2+) signals are ubiquitous. Most intracellular Ca2+ signals involve the release of Ca2+ from the endoplasmic reticulum (ER) through Inositol 1,4,5-Trisphosphate Receptors (IP3Rs). The non-uniform spatial ...
Adaptive spectral processing algorithm for staggered signals in weather radars
(Institution of Engineering and Technology, 2020-11)
A spectral algorithm for processing staggered-pulse repetition time (SPRT) signals in weather radar is introduced. It includes new approaches for ground clutter filter and hydrometeor spectral moments estimation. The ...