Buscar
Mostrando ítems 61-70 de 89
Closo-Carboranyl- and Metallacarboranyl [1,2,3]triazolyl-Decorated Lapatinib-Scaffold for Cancer Therapy Combining Tyrosine Kinase Inhibition and Boron Neutron Capture Therapy
(MPDI, 2020-06)
One of the driving forces of carcinogenesis in humans is the aberrant activation of receptors; consequently, one of the most promising mechanisms for cancer treatment is receptor inhibition by chemotherapy. Although a ...
N-propyl-2,2-diphenyl-2-hydroxyacetamide, a novel α-hydroxyamide with anticonvulsant, anxiolytic and antidepressant-like effects that inhibits voltage-gated sodium channels
(Elsevier Science, 2018-01)
In patients with epilepsy, anxiety and depression are the most frequent psychiatric comorbidities but they often remain unrecognized and untreated. We report herein the antidepressant-like activity in two animal models, ...
Characterization of the B-Raf interactome in mouse hippocampal neuronal cells
(Elsevier Science, 2011-02)
B-Raf links a variety of extracellular stimuli downstream of cell surface receptors, constituting a determining factor in the ability of neurons to activate ERK. A detailed study of the B-Raf interactome is necessary to ...
Mecanismos cerebrales de reforzamiento del alcohol. II. Bases neuroquímicas: papel del sistema opioide
(Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, 1999)
Temporal dissociation between sodium depletion and sodium appetite appearance: Involvement of inhibitory and stimulatory signals
(Pergamon-Elsevier Science Ltd, 2015-06)
Our aim was to analyze the participation of inhibitory and stimulatory signals in the temporal dissociation between sodium depletion (SD) induced by peritoneal dialysis (PD) and the appearance of sodium appetite (SA), ...
EFECTO DEL MONTELUKAST SÓDICO SOBRE LA PRESIÓN ARTERIAL PULMONAR EN POLLOS DE CARNE.
(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria, 2000)
Efectos de las hormonas tiroideas sobre la función ováricaEffects of thyroid hormones on ovarian function
(Sociedad Argentina de Endocrinología Ginecológica y Reproductiva, 2010-08)
Las disfunciones tiroideas son frecuentes en mujeres en edad reproductiva y son una causa común de infertilidad, fertilidad subnormal, abortos espontáneos, problemas en el embarazo y parto prematuro. Se asocian con ...
TGF-β1 mediates cell proliferation and development of hepatocarcinogenesis by downregulating Deiodinase 1 expression
(Medicina (Buenos Aires), 2021-06)
La desregularización de la deiodinasa 1, mediada por TGF-b1, impulsa la proliferación celular y el desarrollo de hepatogénesis. El hepatocarcinoma (HCC) es un tumor hepático primario. El hexaclorobenceno (HCB) es un disruptor ...
Farmacoeconomía e Investigación de Resultados en el Síndrome de Intestino Irritable: Revisión de la evidencia con Tegaserod
(Sociedad de Gastroenterología del Perú, 2006)