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Inactivation of Herpes Simplex Virus by Photosensitizing Anthraquinones Isolated from Heterophyllaea pustulata
(Georg Thieme Verlag Kg, 2021-02)
Heterophyllaea pustulata is a phototoxic plant from Argentina. Aerial parts extracts, high in photosensitizing anthraquinones, have shown in vitro antiviral activity. The purpose of this study was to study the antiherpetic ...
A synthetic stigmastane displays antiadenoviral activity and reduces the inflammatory response to viral infection
(Elsevier Science, 2020-09)
Although human adenovirus (ADV) infections are mild and self-limited in immunocompetent individuals, they can be severe and life-threatening in immunocompromised patients. Despite their significant clinical impact, there ...
The interplay between viperin antiviral activity, lipid droplets and Junín mammarenavirus multiplication
(Academic Press Inc Elsevier Science, 2018-01)
Junín arenavirus infections are associated with high levels of interferons in both severe and fatal cases. Upon Junín virus (JUNV) infection a cell signaling cascade initiates, that ultimately attempts to limit viral ...
Antiherpes virus activities of new 6-19 carbon-bridged steroids and some synthetic precursors
(International Medical Press, 2003-09)
Three synthetic 6,19-carbon bridged steroids: 3β,20β -diacetyloxy-5α-chloro-19a(R)-hydroxy-6,19-methanopregnane, 3β,20β-diacetyloxy-5α-chloro-6,19-methanopregnane, 6,19-methanopregn-4-ene-3,20-dione and four synthetic ...
In vitro and in vivo antiherpetic activity of three new synthetic brassinosteroid analogues
(Elsevier Science Inc, 2004-10)
Brassinosteroids are a novel group of steroids that appear to be ubiquitous in plants and are essential for normal plant growth and development. It has been previously reported that brassinosteroid analogues exert an ...
New immunobiotics from highly proteolytic Lactobacillus delbrueckii strains: their impact on intestinal antiviral innate immune response
(Wageningen Academic Publishers, 2020-08)
Proteolytic starter cultures with intrinsic immunomodulatory activities are desirably features for the development of functional foods, which would significantly reduce the cost of their production (one-strain starter) ...
Acridones As Antiviral Agents: Synthesis, Chemical and Biological Properties
(Bentham Science Publishers, 2013)
Toward wide-spectrum antivirals against coronaviruses: Molecular characterization of SARS-CoV-2 NSP13 helicase inhibitors
(Science Advances is the American Association for the Advancement of Science, 2022)
Artificial microRNAs as antiviral strategy to FMDV: structural implications of target selection
(2014-04)
RNA interference (RNAi) appears as a promising strategy to control virus replication. While the antiviral power of short-hairpin RNAs or small-interfering RNAs against FMDV has been demonstrated widely, safer RNAi effectors ...
Hepatitis C Virus (HCV) clearance after treatment with direct-acting antivirals in human immunodeficiency virus (HIV)-HCV coinfection modulates systemic immune activation and HIV transcription on antiretroviral therapy
(Oxford University Press, 2020-05)
Background. Hepatitis C virus (HCV) coinfection among people with human immunodeficiency virus (HIV) might perturb immune function and HIV persistence. We aimed to evaluate the impact of HCV clearance with direct-acting ...