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Target-Pathogen: A structural bioinformatic approach to prioritize drug targets in pathogens
(Oxford University Press, 2018-01)
Available genomic data for pathogens has created new opportunities for drug discovery and development to fight them, including new resistant and multiresistant strains. In particular structural data must be integrated with ...
Using already solved cases of a mass disaster event for prioritizing the search among remaining victims: a Bayesian approach
(Nature, 2020-03-19)
This work presents a new method for assisting in the identification process of missing persons in several contexts, such as enforced disappearances. We apply a Bayesian technique to incorporate non-genetic variables in the ...
Prioritizing phylogenetic diversity captures functional diversity unreliably
(Nature, 2019-02)
In the face of the biodiversity crisis, it is argued that we should prioritize species in order to capture high functional diversity (FD). Because species traits often reflect shared evolutionary history, many researchers ...
Computational prediction of nsSNPs effects on protein function and structure, a prioritization approach for further in vitro studies applied to bovine GSTP1
(Elsevier Science Inc, 2018-12)
The development of high-throughput technologies in the last decade produced an exponential increase in the amount of biological data available. The case of redox biology and apoptosis is not an exception, and nowadays there ...
Diversity and dynamics in larval digenean assemblages parasitizing Heleobia parchappii in a freshwater shallow lake from the Southeastern Pampa plain, Argentina
(Cambridge University Press, 2021-10)
Digeneans have important roles within ecosystems, however, it is estimated that only 14% of the species have been described. Therefore, before being able to detail their role, digenean species identification and the diversity ...
Stress factors and food purchase prioritization during the pandemic of coronavirus disease 2019
(Elsevier LtdNL, 2024)
Background: The pandemic of coronavirus disease 2019 (COVID-19) pandemic confinement has an impact on stress levels, which causes changes in food purchase and consumption behaviors. The objective of this study is to associate ...
Prioritization of IT projects through process modeling and use of the PROMETHEE methodPriorización de proyectos de TI mediante el modelado del proceso y la utilización del método PROMETHEEPriorização de projetos de TI através da modelagem do processo e utilização do método PROMETHEE
(Escola Brasileira de Administração Pública e de Empresas - Fundação Getulio Vargas, 2018)
Assessing the utility of conserving evolutionary history
(Wiley Blackwell Publishing, Inc, 2019-10)
It is often claimed that conserving evolutionary history is more efficient than species-based approaches for capturing the attributes of biodiversity that benefit people. This claim underpins academic analyses and ...