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Two-dimensional brain microtubule structures behave as memristive devices
(Nature, 2019-08)
Microtubules (MTs) are cytoskeletal structures that play a central role in a variety of cell functions including cell division and cargo transfer. MTs are also nonlinear electrical transmission lines that produce and conduct ...
Reliable Genetic Labeling of Adult-Born Dentate Granule Cells Using Ascl1CreERT2 and GlastCreERT2 Murine Lines
(Society for Neuroscience, 2015-11)
Newly generated dentate granule cells (GCs) are relevant for input discrimination in the adult hippocampus. Yet, their precise contribution to information processing remains unclear. To address this question, it is essential ...
Direction selective neurons responsive to horizontal motion in a crab reflect an adaptation to prevailing movements in flat environments
(Society for Neuroscience, 2020-07-15)
All animals need information about the direction of motion to be able to track the trajectory of a target (prey, predator, cospecific) or to control the course of navigation. This information is provided by direction ...
Computation of object approach by a system of visual motion-sensitive neurons in the crab Neohelice
(American Physiological Society, 2014-09)
.Similar to most visual animals, crabs perform proper avoidance responses to objects directly approaching them. The monostratified lobula giant neurons of type 1 (MLG1) of crabs constitute an ensemble of 14–16 bilateral ...
Association between antiarrhythmic, electrophysiological and antioxidative effects of melatonin in ischemia/reperfusion
(Molecular Diversity Preservation International, 2019-12-15)
Melatonin is assumed to confer cardioprotective action via antioxidative properties. We evaluated the association between ventricular tachycardia and/or ventricular fibrillation (VT/VF) incidence, oxidative stress, and ...
Early NMDA receptor ablation in interneurons causes an activity-dependent E/I imbalance in vivo in prefrontal cortex pyramidal neurons of a mouse model useful for the study of schizophrenia
(Oxford University Press, 2021-09)
Altered Excitatory/Inhibitory (E/I) balance of cortical synaptic inputs has been proposed as a central pathophysiological factor for psychiatric neurodevelopmental disorders, including schizophrenia (SZ). However, direct ...
Lipid bilayer-atomic force microscopy combined platform records simultaneous electrical and topological changes of the TRP channel Polycystin-2 (TRPP2)
(Public Library of Science, 2018-08)
Ion channels are transmembrane proteins that mediate ion transport across biological membranes. Ion channel function is traditionally characterized by electrical parameters acquired with techniques such as patch-clamping ...
Regulation of the Cardiac Sodium/Bicarbonate cotransporter by Angiotensin II: potential contribution to structural, ionic and electrophysiological Myocardial remodelling
(Bentham Science Publishers, 2013-02)
The sodium/ bicarbonate cotransporter (NBC) is, with the Na+ /H+ exchanger (NHE), an important alkalinizing mechanism that maintains cellular intracellular pH (pHi). In the heart exists at least three isoforms of NBC, one ...
Undirected singing rate as a non-invasive tool for welfare monitoring in isolated male zebra finches
(Public Library of Science, 2020-08)
Research on the songbird zebra finch (Taeniopygia guttata) has advanced our behavioral, hormonal, neuronal, and genetic understanding of vocal learning. However, little is known about the impact of typical experimental ...
Global REACH: assessment of brady-arrhythmias in andeans and lowlanders during apnea at 4330 m
(Frontiers Media, 2019)
Background: Ascent to altitude increases the prevalence of arrhythmogenesis in low-altitude dwelling populations (Lowlanders). High altitude populations (i.e., Nepalese Sherpa) may have arrhythmias resistant adaptations ...