Buscar
Mostrando ítems 31-40 de 40
Antiprogestins in breast cancer treatment: Are we ready?
(BioScientifica, 2012-06)
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in females worldwide. It is accepted that breast cancer is not a single disease, but instead constitutes a spectrum of tumor ...
Oligosaccharyltransferase inhibition reduces receptor tyrosine kinase activation and enhances glioma radiosensitivity
(American Association for Cancer Research, 2019-01)
Purpose: Parallel signaling reduces the effects of receptor tyrosine kinase (RTK)–targeted therapies in glioma. We hypothesized that inhibition of protein N-linked glycosylation, an endoplasmic reticulum co- and posttranslational ...
Epidermal growth factor receptor activity upregulates lactate dehydrogenase a expression, lactate dehydrogenase activity, and lactate secretion in cultured ib3-1 cystic fibrosis lung epithelial cells
(National Research Council Canada-NRC Research Press, 2021-01)
Cystic fibrosis (CF) is caused by mutations in the CFTR gene. It has been postulated that a reduced HCO3 − transport in CF through CFTR may lead to a decreased airway surface liquid (ASL) pH. In contrast, others have ...
Detección del receptor tipo 2 del factor de crecimiento epidérmico humano (her2/neu): inmunohistoquímica en carcinomas de mama
(Colegio de Médicos y Cirujanos de Costa Rica, 2015)
A molecular portrait of high-grade Ductal Carcinoma in situ
(American Association For Cancer Research, 2015-09)
Ductal carcinoma in situ (DCIS) is a noninvasive precursor lesion to invasive breast carcinoma. We still have no understanding on why only some DCIS lesions evolve to invasive cancer whereas others appear not to do so ...
Impact of histamine H4 receptor deficiency on the modulation of T cells in a murine breast cancer model
(Springer, 2020-07)
Background: The histamine H4 receptor (H4R) is preferentially expressed in immune cells and is a potential therapeutic target for inflammatory and autoimmune diseases. This study aimed at further exploring the role of H4R ...
Beth Levine in memoriam
(Landes Bioscience, 2020-07)
Beth Levine was born on 7 April 1960 in Newark, New Jersey. She went to college at Brown University where she received an A.B. Magna Cum Laude, and she attended medical school at Cornell University Medical College, receiving ...