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Analogues of Human Granulysin as Antimycobacterial Agents
(Springer, 2019-06)
Antimicrobial peptides are essential components of innate defense mechanisms and make promising candidates for novel anti-infective agents. The advantages of these peptides in clinical applications include their potential ...
Potato Snakin-1: an antimicrobial player of the trade-off between host defense and development
(Springer, 2020-07)
Snakin-1 (SN1) from potato is a cysteine-rich antimicrobial peptide with high evolutionary conservation. It has 63 amino acid residues, 12 of which are cysteines capable of forming six disulfide bonds. SN1 localizes in the ...
Obtaining an Ent35-MccV derivative with mutated hinge region that exhibits increased activity against listeria monocytogenes and escherichia coli
(Springer, 2019-11)
The present paper describes the generation of derivatives from the hybrid peptide called Ent35-MccV, active against Gram-positive and Gram-negative bacteria. This peptide has a triple glycine hinge region between enterocin ...
Disruption of Saccharomyces cerevisiae by Plantaricin 149 and investigation of its mechanism of action with biomembrane model systems
(Elsevier Science, 2009-10)
The action of a synthetic antimicrobial peptide analog of Plantaricin 149 (Pln149a) against Saccharomyces 24 ^ cerevisiae and its interaction with biomembrane model systems were investigated. Pln149a was shown to 25 inhibit ...
Biological activity of antibacterial peptides matches synergism between electrostatic and non electrostatic forces
(Elsevier Science, 2014-07)
Substitution of Ala 108 and Ala 111 in the 107–115 human lysozyme (hLz) fragment results in a 20- fold increased anti-staphylococcal activity while its hemolytic activity becomes significant (30%) at very high concentrations. ...
Alfalfa snakin-1 prevents fungal colonization and probably coevolved with rhizobia
(BMC Plant Biology, 2014-09-17)
Background: The production of antimicrobial peptides is a common defense strategy of living cells against a wide range of pathogens. Plant snakin peptides inhibit bacterial and fungal growth at extremely low concentrations. ...
Potato snakin‑1: an antimicrobial player of the trade‑off between host defense and development
(Springer, 2020-07)
Snakin-1 (SN1) from potato is a cysteine-rich antimicrobial peptide with high evolutionary conservation. It has 63 amino acid residues, 12 of which are cysteines capable of forming six disulfide bonds. SN1 localizes in the ...
Transgenic citrange troyer rootstocks overexpressing antimicrobial potato snakin-1 show reduced citrus canker disease symptoms
(Elsevier, 2020-12)
Citrus canker is a major disease caused by Xanthomonas citri pv. citri. Snakin-1 is an antimicrobial peptide, which was previously shown to be effective against different bacterial and fungal diseases in potato, wheat and ...
Trichogin GA IV Alignment and Oligomerization in Phospholipid Bilayers
(Wiley VCH Verlag, 2019-05)
Trichogin GA IV is a short peptaibol with antimicrobial activity. This uncharged, but amphipathic, sequence is aligned at the membrane interface and undergoes a transition to an aggregated state that inserts more deeply ...