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Mechanical stability of lipid membranes decorated with dextran sulfate
(American Chemical Society, 2018-09)
Lipid vesicles decorated with polysaccharides have been proposed as vehicles for drug delivery because the polymers confer to the vesicles an enhanced stability, increasing the probability of the drug for reaching the ...
Reorganization of Azospirillum brasilense cell membrane is mediated by lipid composition adjustment to maintain optimal fluidity during water deficit
(Wiley Blackwell Publishing, Inc, 2016-01)
Aims: We study the Azospirillum brasilense tolerance to water deficit and the dynamics of adaptive process at the level of the membrane. Methods and Results: Azospirillum brasilense was exposed to polyethylene glycol (PEG) ...
Host membrane glycosphingolipids and lipid microdomains facilitate Histoplasma capsulatum internalisation by macrophages
(Wiley Blackwell Publishing, Inc, 2019-03)
Recognition and internalisation of intracellular pathogens by host cells is a multifactorial process, involving both stable and transient interactions. The plasticity of the host cell plasma membrane is fundamental in this ...
Coffee consumption increases the antioxidant capacity of plasma and has no effect on the lipid profile or vascular function in healthy adults in a randomized controlled trial
(American Society for NutritionAlimentación y Nutrición HumanaGrupo de Investigación en Sustancias Bioactivas (GISB)Springfield, Estados Unidos, 2019)
The moonlighting protein c-Fos activates lipid synthesis in neurons, an activity that is critical for cellular differentiation and cortical development
(American Society for Biochemistry and Molecular Biology, 2020-06-26)
Differentiation of neuronal cells is crucial for the development and function of the nervous system. This process involves high rates of membrane expansion, during which the synthesis of membrane lipids must be tightly ...
The Synaptotagmin-1 C2B Domain Is a Key Regulator in the Stabilization of the Fusion Pore
(American Chemical Society, 2020-11)
Fusion pores serve as an effective mechanism to connect intracellular organelles and release vesicle contents during exocytosis. A complex lipid rearrangement takes place as membranes approximate, bend, fuse, and establish ...
Interferon-Β lipofection II: Mechanisms involved in cell death and bystander effect induced by cationic lipid-mediated interferon-Β gene transfer to human tumor cells
(Nature Publishing Group, 2012-06)
We evaluated the cytotoxic effects (apoptosis, necrosis and early senescence) of human interferon-B (hIFNB) gene lipofection. The cytotoxicity of hIFNB gene lipofection resulted equivalent to that of the corresponding ...
Fatty acid signaling mechanisms in neural cells: Fatty acid receptors
(Frontiers Media, 2019-04-24)
Fatty acids (FAs) are typically associated with structural and metabolic roles, as they can be stored as triglycerides, degraded by β-oxidation or used in phospholipids’ synthesis, the main components of biological membranes. ...
Mechanisms of canalicular transporter endocytosis in the cholestatic rat liver
(Elsevier Science, 2018-04)
Impaired canalicular secretion due to increased endocytosis and intracellular retention of canalicular transporters such as BSEP and MRP2 is a main, common pathomechanism of cholestasis. Nevertheless, the mechanisms governing ...