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In vitro and in vivo activity of benzocphenanthridines against Leishmania amazonensis
(Georg Thieme Verlag, 2014)
Seven benzo[c]phenanthridines, synthetic or isolated from Zanthoxylum rhoifolium root bark, were evaluated against Leishmania amazonensis axenic amastigotes. Five of them were considered leishmanicidal, with IC50 values ...
Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines
(Elsevier, 2015)
A series of original 2-phenyl-3-(pyridin-4-yl)imidazo[1,2-a]pyrazines and the 3-iodo precursors, bearing a polar moiety at the C-8 position, was synthesized and evaluated for their antileishmanial activities. Two derivatives ...
Anti-Taenia solium monoclonal antibodies for the detection of parasite antigens in body fluids from patients with neurocysticercosis
(Elsevier, 2016)
Neurocysticercosis (NCC), an infection of the brain by Taenia solium (Ts) cysts, is the most common cause of adult-onset epilepsy in developing countries. Serological testing consists primarily of varying methods to detect ...
Comparison between Trichinella patagoniensis and Trichinella spiralis infection in BALB/c mice
(Elsevier Science, 2020-10)
In Argentina, trichinellosis is an endemic disease acquired mainly through consumption of raw pork infected with nematodes larvae from the Trichinella genus. For years, the only species involved in outbreaks in humans and ...
Involvement of extracellular matrix proteins in the course of experimental paracoccidioidomycosis
(Federation of European Microbiological SocietiesMicología Médica y ExperimentalMicrobiología MolecularOxford, Inglaterra, 2021)
Subchronic toxicological evaluation of brea gum (Parkinsonia preacox) as a food additive in BALB/c mice
(Taylor & Francis, 2009-09)
Brea gum is a phloematic exudate from Parkinsonia praecox, an autoctonous tree that grows in the arid areas of Argentina. In this work, we propose its potentiality as a food additive. However, as no toxicological safety ...