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8-Hydroxyquinoline platinum(ii) loaded nanostructured lipid carriers: synthesis, physicochemical characterization and evaluation of antitumor activity
(Royal Society of Chemistry, 2021-01-08)
Every year the incidence of cancer and the death rate are increasing worldwide. The drug 8-hydroxyquinoline platinum(II) [PtCl(8-O-quinoline)(dmso)] (8HQ-Pt) has been identified as a promising antitumor complex. Nanostructured ...
Hyaluronan degrading silica nanoparticles for skin cancer therapy
(Royal Society of Chemistry, 2013-07)
We report the first nanoformulation of Hyaluronidase (Hyal) and its enhanced adjuvant effect over the free enzyme. Hyaluronic acid (HA) degrading enzyme Hyal was immobilized on 250 nm silica nanoparticles (SiNP) maintaining ...
Use of Ionic Liquids-like Surfactants for the Generation of Unilamellar Vesicles with Potential Applications in Biomedicine
(American Chemical Society, 2019-10-30)
The goal of this work is to understand the influence of the counterion nature on the organized systems formed by 1,4-bis-2-ethylhexylsulfosuccinate surfactants in aqueous solutions and how these aggregates will influence ...
Liposome fusion mediated by hydrophobic magnetic nanoparticles stabilized with oleic acid and modulated by an external magnetic field
(American Chemical Society, 2021-02)
Membrane fusion is considered relevant in countless scientific areas and biotechnological processes, ranging from vital life events to biomedicine, pharmaceuticals, and materials engineering, among others. In this study, ...
Spontaneous formation of unilamellar vesicles based on the surfactant 1-methylimidazolium bis-(2-ethylhexyl) phosphate, evaluated as a function of pH and in saline solution
(Elsevier Science, 2020-12)
In this work, we report the formation of unilamellar vesicles in water based on the protic ionic liquid-surfactant 1-methylimidazolium bis-(2-ethylhexyl) phosphate (imim-DEHP) explored under different experimental conditions ...
Phosphorus as a promoter of a nickel catalyst to obtain 1-phenylethanol from chemoselective hydrogenation of acetophenone
(Elsevier, 2019-06)
Two catalysts were prepared using monodisperse pre-synthetized nanoparticles of metallic nickel and nickel phosphides with the same average diameter. Both nanoparticles species were deposited on the same support: mesoporous ...
Photopolymerization of acrylamide Initiated by the three-component system Safranine/Triethanolamine/ Diphenyliodonium chloride: The effect of the aggregation of the salt
(John Wiley & Sons Inc, 2004-10)
The effects of diphenyliodonium chloride (DPI) on the polymerization of acrylamide photoinitiated by the dye safranine with triethanolamine as a coinitiator were investigated in aqueous solutions. The salt notably increased ...
Controlling the generation of bilayer and multilayer vesicles in block copolymer/epoxy blends by a slow photopolymerization process
(Royal Society of Chemistry, 2017-09)
Vesicles are a highly attractive morphology to achieve in micellar dispersions of block copolymers (BCP) in epoxy thermosets due to the fact that small amounts can affect a large volume fraction of the matrix, a fact that ...
A study of the complex interaction between poly allylamine hydrochloride and negatively charged poly (N-isopropylacrylamide-co-methacrylic acid) microgels
(Royal Society of Chemistry, 2020-01)
Negatively charged poly(N-isopropylacrylamide-co-methacrylic acid) (P(NIPAm-co-MAA)) microgels undergo size changes in response to changes in temperature and pH. Complexation of these microgels with positively charged ...
Combination of protic ionic liquid-like surfactant and biocompatible solvents to generate environmentally friendly anionic reverse micelles
(Royal Society of Chemistry, 2019-06)
In the present work we have formulated environmentally friendly anionic reverse micelles (RMs) by the combination of a protic ionic liquid-like surfactant with biocompatible nonpolar solvents. Thus, the protic ionic liquid, ...