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Mostrando ítems 11-20 de 40
Caracterización de cultivos neuronales de hipocampo murino como modelo de estudio de la señalización NRGs/ErbB4
(Instituto Tecnológico de Costa Rica, 2022)
Neuregulin signaling is a mechanism of therapeutic resistance in head and neck squamous cell carcinoma
(American Association for Cancer Research, 2019-08)
EGFR signaling confers resistance to radiotherapy and is a validated target in head and neck squamous cell carcinoma (HNSCC). The inhibition of EGFR in combination with radiotherapy improves local control and overall ...
MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1
(Nature Publishing Group, 2016-03)
ErbB-2 amplification/overexpression accounts for an aggressive breast cancer (BC) subtype (ErbB-2-positive). Enhanced ErbB-2expression was also found in gastric cancer (GC) and has been correlated with poor clinical outcome. ...
Neuregulin 1-erbB signaling is necessary for normal myelination and sensory function.
(Society for Neuroscience, 2006-12)
To investigate the role of erbB signaling in the interactions between peripheral axons and myelinating Schwann cells, we generated transgenic mice expressing a dominant-negative erbB receptor in these glial cells. Mutant ...
Detection of gene amplification in MYCN, C-MYC, MYCL1, ERBB2, EGFR, AKT2, and human papilloma virus in samples from cervical smear normal cytology, intraepithelial cervical neoplasia (CIN I, II, III), and cervical cancer
Introducción: El cáncer cervical es el segundo cáncer más importante en mujeres a nivel mundial y es la segunda causa
de muerte por cáncer en mujeres. Se ha demostrado que el proceso de carcinogénesis cervical presenta ...
Detection of gene amplification in MYCN, C-MYC, MYCL1, ERBB2, EGFR, AKT2, and human papilloma virus in samples from cervical smear normal cytology, intraepithelial cervical neoplasia (CIN I, II, III), and cervical cancer
Introducción: El cáncer cervical es el segundo cáncer más importante en mujeres a nivel mundial y es la segunda causa
de muerte por cáncer en mujeres. Se ha demostrado que el proceso de carcinogénesis cervical presenta ...
One-class models for validation of miRNAs and ERBB2 gene interactions based on sequence features for breast cancer scenarios
(Korean Institute of Communication SciencesKR, 2021)
One challenge in miRNA–genes–diseases interaction studies is that it is challenging to find labeled data that indicate a positive or negative relationship between miRNA and genes. The use of one-class classification methods ...
Estudio de variables y perfil inmunohistoquímico en pacientes con carcinoma de células renales
(Facultad de Medicina de la UNNE, 2021)
Heregulin Activity Assays for Residual Testing of Cell Therapy Products
(Springer, 2021-11)
Background: Heregulin is a ligand for the protooncogene product ErbB/HER that acts as a key mitogenic factor for human Schwann cells (hSCs). Heregulin is required for sustained hSC growth in vitro but must be thoroughly ...