Buscar
Mostrando ítems 11-20 de 26
Cc2d1a, a C2 domain containing protein linked to nonsyndromic mental retardation, controls functional maturation of central synapses
(American Physiological Society, 2011-04)
Cc2d1a is an evolutionarily conserved protein composed of NH2-terminal Drosophila melanogaster 14 domain (DM14) domains and a COOH-terminal C2 domain. Human patients with homozygotic mutation in the gene suffer from ...
Evolution of genomes, host shifts and the geographic spread of SARS-CoV and related coronaviruses
(Wiley Blackwell Publishing, Inc, 2008-04)
Severe acute respiratory syndrome (SARS) is a novel human illness caused by a previously unrecognized coronavirus (CoV) termed SARS-CoV. There are conflicting reports on the animal reservoir of SARS-CoV. Many of the groups ...
Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-d-glucuronide in rat intestine and Caco-2 cells
(Springer, 2017-10)
Multidrug resistance-associated protein 2 (MRP2) is an ATP-dependent transporter expressed at the brush border membrane of the enterocyte that confers protection against absorption of toxicants from foods or bile. Acute, ...
Metallothionein 1G and zinc sensitize human colorectal cancer cells to chemotherapy
(American Association for Cancer Research, 2014-03)
Metallothioneins (MT) are a family of low molecular weight proteins that are silenced during colorectal cancer progression, mainly through epigenetic mechanisms, and this loss is associated with poor survival. In this ...
Anticuerpos neutralizantes, nuevas pruebas de laboratorio contra el SARS-CoV-2
(Colegio Médico del Perú, 2021-12-24)
Introducción: En la presente revisión conoceremos los detalles de esta nueva prueba de laboratorio, utilizada para cuantificar los anticuerpos neutralizantes contra el SARS-CoV-2. Esta prueba diagnóstica comienza ...
SARS-CoV-2 vaccines: evolution and escapeVacunas SARS-CoV-2: evolución y escape
(Universidad de Córdoba, 2021)
Potent and selective inhibitors for M32 metallocarboxypeptidases identified from high-throughput screening of anti-kinetoplastid chemical boxes
(Public Library of Science, 2019-08)
Enzymes of the M32 family are Zn-dependent metallocarboxypeptidases (MCPs) widely distributed among prokaryotic organisms and just a few eukaryotes including Trypanosoma brucei and Trypanosoma cruzi, the causative agents ...
Self-assembled lipids for food applications: A review
(Elsevier Science, 2020-11)
Lipids play an important role in human nutrition. Several foodstuffs can be manufactured from the simple, compound and derived lipids. In particular, the use of self-assembled lipids (SLs, e.g. self-assembled L-α-lecithin) ...
Characterization and modulation of microglial phenotypes in an animal model of severe sepsis
(Journal of Cellular and Molecular Medicine, 2019)