Buscar
Mostrando ítems 61-70 de 211
Comparative study of three structurally related acid polyelectrolytes as carriers of basic drugs: Carbomer, Eudragit L 100 and Eudragit S 100
(Taylor & Francis Ltd, 2010-05)
A detailed description of equilibrium and drug release properties of aqueous dispersions of complexes of model basic drugs (D) with three structurally related acid polyelectrolytes (PE) is reported. Thus, equilibrium ...
Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility
(Cell Press, 2019-09-19)
Genes are transcribed in a discontinuous pattern referred to as RNA bursting, but the mechanisms regulating this process are unclear. Although many physiological signals, including glucocorticoid hormones, are pulsatile, ...
A caged nicotine with nanosecond range kinetics and visible light sensitivity
(Elsevier Science Inc, 2010-12)
We report the synthesis, characterization and applications of a ruthenium-bipyridine based caged nicotine. The complex [Ru(bpy)2(nic)2]2+ (where bpy=2,2' bipyridine and nic=nicotine (3-[(2S)-1-methylpyrrolidin-2-yl] ...
Design and in vitro evaluation of effervescent gastric floating drug delivery systems of propanolol HCl
(Universidad del Zulia, 2012)
Human erythrocytes release ATP by a novel pathway involving VDAC oligomerization independent of pannexin-1
(Springer Nature, 2018-12)
We previously demonstrated that the translocase protein TSPO2 together with the voltage-dependentanion channel (VDAC) and adenine nucleotide transporter (ANT) were involved in a membrane transportcomplex in human red blood ...
45S5 Bioglass® concentrations modulate the release of vancomycin hydrochloride from gelatin–starch films: evaluation of antibacterial and cytotoxic effects
(Springer, 2016-11)
The aim of this work was to evaluate the release profile of vancomycin hydrochloride (VC), as well as the degradation, in vitro antistaphylococcal effect and cytotoxicity in MG-63 osteoblast-like cells of gelatin–starch ...
Mechanism of Sulfide Binding by Ferric Hemeproteins
(American Chemical Society, 2018-07)
The reaction of hydrogen sulfide (H2S) with hemeproteins is a key physiological reaction; still, its mechanism and implications are not completely understood. In this work, we propose a combination of experimental and ...
Niosomes encapsulated in biohydrogels for tunable delivery of phytoalexin resveratrol
(Royal Society of Chemistry, 2019-02)
A series of biohydrogels based on mixtures of kappa-carrageenan (κ-carrageenan, κ-C) and gelatin were evaluated as potential soft delivery vehicles for the encapsulation and subsequent release of non-ionic surfactant ...