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Diketopyrrolopyrrole-fullerene C60 architectures as highly efficient heavy atom-free photosensitizers: Synthesis, photophysical properties and photodynamic activity
(Royal Society of Chemistry, 2020-02)
Chromophore-fullerene C60 hybrids possess interesting properties that enable them to act as heavy atom-free photosensitizers and reactive oxygen species (ROS) producers. Here, two new diketopyrrolopyrrole-C60 conjugates ...
Porphyrins containing basic aliphatic amino groups as potential broad-spectrum antimicrobial agents
(Elsevier Science, 2018-12)
New porphyrin derivatives bearing basic aliphatic amino groups were synthesized from the condensation of meso-4-[(3-N,N-dimethylaminopropoxy)phenyl]dipyrromethane, pentafluorobenzaldehyde and 4-(3-N,N-dimethylaminopropox ...
Photodynamic inactivation mediated by 5-aminolevulinic acid of bacteria in planktonic and biofilm forms
(Pergamon-Elsevier Science Ltd, 2020-07)
Bacterial photodynamic inactivation (PDI) employing endogenous production of porphyrins from 5-aminolevulinic acid (ALA) – named ALA-PDI-, is a new promising tool to achieve bacteria control in non-spread infections. The ...
Antimicrobial effects of ZnPc delivered into liposomes on multidrug resistant (MDR)‐ mycobacterium tuberculosis
(Wiley-Blackwell, 2019-09)
Tuberculosis is one of the most important global health problems. Multidrug resistant (MDR)-tuberculosis is caused by Mycobacterium tuberculosis (M. tuberculosis) resistant to the first line drugs (rifampin-isoniazid). ...
Natural anthraquinones as novel photosentizers for antiparasitic photodynamic inactivation
(Elsevier Gmbh, 2019-08)
Cutaneous leishmaniasis (CL) is a vector-borne disease caused by obligate protist parasites from the genus Leishmania. The potential toxicity as well as the increased resistance of standard treatments has encouraged the ...
Silica nanoparticles embedded with water insoluble phthalocyanines for the photoinactivation of microorganisms
(Elsevier Science, 2018-09)
Silica nanoparticles (SiNPs) embedded with Zn(II) 2,9,16,23-tetrakis(methoxy)phthalocyanine (SiNPZnPcOCH3), Zn(II) 2,9,16,23-tetrakis(4-pyridyloxy) phthalocyanine (SiNPZnPcOPy) and Zn(II) 2,9,16,23-tetrakis(t-butyl) ...
Superhydrophobic surfaces as a source of airborne singlet oxygen through free space for photodynamic therapy
(American Chemical Society, 2020-04)
A superhydrophobic (SH) sandwich system has been developed to enable "contact-free" airborne singlet oxygen (1O2) delivery to a water droplet. The contact-free feature means that the sensitizer is physically separated from ...
meso-Acetoxymethyl BODIPY dyes for photodynamic therapy: improved photostability of singlet oxygen photosensitizers
(Royal Society of Chemistry, 2016-12)
We report two BODIPY based photosensitizers (Br2BOAc and I2BOAc) featuring an acetoxymethyl substituent at the meso-position. These photosensitizers show improved photostability against singlet oxygen, when compared to a ...
Photodegradation and phototoxicity of antibacterial agents and the new alternatives for the photo-inactivation of microorganisms
(Facultad Experimental de Ciencias de la Universidad del Zulia, 2011)
Preclinical investigation of Methylene Blue-mediated Antimicrobial Photodynamic Therapy on Leishmania parasites using Real-Time Bioluminescence
(Wiley Blackwell Publishing, Inc, 2020-05)
Cutaneous leishmaniasis (CL) is a neglected disease that promotes destructive lesions. Difficulties in treatment are related to accessibility of drugs, resistance and toxicity. Antimicrobial photodynamic therapy (APDT) has ...