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BODIPYs bearing a dimethylaminopropoxy substituent for imaging and photodynamic inactivation of bacteria
(Elsevier Science SA, 2020-11)
A new BODIPY (BDP 1) bearing a dimethylaminopropoxy group attached to a phenylene unit was synthesized. This compound was brominated to obtain the halogenated analog BDP 2, which was designed to enhance the photodynamic ...
Immobilization of alkyl-pterin photosensitizer on silicon surfaces through in situ SN2 reaction as suitable approach for photodynamic inactivation of Staphylococcus aureus
(Elsevier Science, 2021-02)
The tuning of surface properties through functionalization is an important field of research with a broad spectrum of applications. Self-assembled monolayers (SAMs) allow the surface tailoring through the adsorption of ...
Light-harvesting antenna and proton-activated photodynamic effect of a novel BODIPY-fullerene C60 dyad as potential antimicrobial agent
(Wiley VCH Verlag, 2019-03)
A covalently linked BODIPY−fullerene C 60 dyad (BDP−C 60 ) was synthesized as a two-segment structure, which consists of a visible light-harvesting antenna attached to an energy or electron acceptor moiety. This structure ...
Sae regulator factor impairs the response to photodynamic inactivation mediated by Toluidine blue in Staphylococcus aureus
(Elsevier Science, 2016-12)
Photodynamic inactivation (PDI) involves the combined use of light and aphotosensitizer, which, in the presence of oxygen, originates cytotoxic species capableof inactivating bacteria. Since the emergence of multi-resistant ...
Inactivation of Herpes Simplex Virus by Photosensitizing Anthraquinones Isolated from Heterophyllaea pustulata
(Georg Thieme Verlag Kg, 2021-02)
Heterophyllaea pustulata is a phototoxic plant from Argentina. Aerial parts extracts, high in photosensitizing anthraquinones, have shown in vitro antiviral activity. The purpose of this study was to study the antiherpetic ...
Photodynamic inactivation of microorganisms sensitized by cationic BODIPY derivatives potentiated by potassium iodide
(Royal Society of Chemistry, 2017-08)
The photodynamic inactivation mediated by 1,3,5,7-tetramethyl-8-[4-(N,N,N-trimethylamino)phenyl]-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 3 and 8-[4-(3-(N,N,N-trimethylamino)propoxy)phenyl]-4,4-difluoro-4-bora-3a,4a-di ...
Resveratrol enhancement staphylococcus aureus survival under levofloxacin and photodynamic treatments
(Elsevier Science, 2017-10)
Reactive oxygen species (ROS) are an efficient tool to eradicate micro-organisms owing to the capacity of these species to damage almost all types of biomolecules and to kill cells. The increase in mechanisms of antimicrobial ...
Mechanistic aspects in the photodynamic inactivation of Candida albicans sensitized by a dimethylaminopropoxy porphyrin and its equivalent with cationic intrinsic charges
(Elsevier Science, 2020-09)
Photocytotoxic effect induced by 5,10,15,20-tetrakis[4-(3-N,N-dimethylaminopropoxy)phenyl]porphyrin (TAPP) and 5,10,15,20-tetrakis[4-(3-N,N,N-trimethylaminepropoxy)phenyl]porphyrin (TAPP+4) was examined in Candida albicans ...
Bacteriochlorin-bis(spermine) conjugate affords an effective photodynamic action to eradicate microorganisms
(Wiley VCH Verlag, 2020-02)
A novel bacteriochlorin bearing two spermine units (BCS) was synthesized from 3,13-dibromo-8,8,18,18-tetramethylbacteriochlorin (BC-Br3,13). The synthesis involved the Suzuki coupling of BC-Br3,13 to obtain a bacteriochl ...
Synthesis, spectroscopic properties and photodynamic activity of Zn(II) phthalocyanine-polymer conjugates as antimicrobial agents
(Pergamon-Elsevier Science Ltd, 2020-07)
Conjugates of Zn(II) phthalocyanine to chitosan (CS) and polyethylenimine (PEI) were synthetized through the following stages: first a phthalonitrile substituted by a (carbomethoxy)phenoxy group (Pn 1) was obtained by ...