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Activación de la respuesta inmune innata y específica en los pacientes con Síndrome Urémico Hemolítico: Papel dual a través de la participación en los mecanismos patogénicos y protectoresActivation of innate and specific immune responses in hemolytic uremic syndrome (HUS)- patients
(Medicina (Buenos Aires), 2006-12)
La función primaria del sistema inmunológico es preservar al individuo sano frente a infinidad de agentes microbianos patógenos o injuriantes. Sin embargo, en determinadas circunstancias los mecanismos agresores normalmente ...
Lymphotropic viruses EBV, KSHV and HTLV in Latin America: Epidemiology and associated malignancies. A literature-based study by the RIAL-CYTED
(Molecular Diversity Preservation International, 2020-08-04)
The Epstein-Barr virus (EBV), Kaposi sarcoma herpesvirus (KSHV) and human T-lymphotropic virus (HTLV-1) are lymphomagenic viruses with region-specific induced morbidity. The RIAL-CYTED aims to increase the knowledge of ...
Second generation BTK inhibitors impair the anti-fungal response of macrophages and neutrophils
(Wiley-liss, div John Wiley & Sons Inc., 2020-04)
BTK inhibitors (BTKi) play a major role in the treatment of Chronic Lymphocytic Leukemia (CLL). Ibrutinib, the first in class BTKi, impairs macrophage and neutrophil functions and also cell-mediated effector mechanisms of ...
Trypanosoma cruzi Infection Is a Potent Risk Factor for Non-alcoholic Steatohepatitis Enhancing Local and Systemic Inflammation Associated with Strong Oxidative Stress and Metabolic Disorders
(Public Library of Science, 2015-02)
The immune mechanisms underlying experimental non-alcoholic steatohepatitis (NASH), and more interestingly, the effect of T. cruzi chronic infection on the pathogenesis of this metabolic disorder are not completely understood. ...
The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands
(Elsevier Science, 2017-05)
HLA-B∗46:01 was formed by an intergenic mini-conversion, between HLA-B∗15:01 and HLA-C∗01:02, in Southeast Asia during the last 50,000 years, and it has since become the most common HLA-B allele in the region. A functional ...
Bacterial DNA activates human neutrophils by a CpG‐independent pathway
(Wiley VCH Verlag, 2003)