Buscar
Mostrando ítems 21-30 de 41
Influence of Acute Myeloid Leukemia Progression on the Prognosis of 831 Patients With Myelodysplastic Syndromes From the Argentine Database
(Elsevier Inc, 2017-11)
In our retrospective review of 831 patients with myelodysplastic syndromes, 158 developed progression with a very poor outcome (median survival after evolution, 3.5 months). The survival of patients with adverse karyotypes ...
CXCL12 is a costimulator for CD4+ T cell activation and proliferation in chronic lymphocytic leukemia patients
(Springer, 2013-01)
Activated T cells from patients with chronic lymphocytic leukemia (CLL) provide survival and proliferative signals to the leukemic clone within lymphoid tissues. Recruitment of both, CLL cells and T lymphocytes, to this ...
Immunoregulatory effects of Lurbinectedin in chronic lymphocytic leukemia
(Springer, 2020-02-13)
Despite significant therapeutic improvements chronic lymphocytic leukemia (CLL) remains an incurable disease and there is a persistent pursuit of new treatment alternatives. Lurbinectedin, a selective inhibitor of active ...
MRP4/ABCC4 expression is regulated by histamine in acute myeloid leukemia cells, determining cAMP efflux
(Wiley Blackwell Publishing, Inc, 2020-05)
Intracellular cAMP (i-cAMP) levels play an important role in acute myeloid leukemia (AML) cell proliferation and differentiation. Its levels are the result of cAMP production, degradation, and exclusion. We have previously ...
MRP4/ABCC4 expression is regulated by histamine in acute myeloid leukemia cells, determining cAMP efflux
(Wiley Blackwell Publishing, Inc, 2020-04)
Intracellular cAMP (i-cAMP) levels play an important role in acute myeloid leukemia (AML) cell proliferation and differentiation. Its levels are the result of cAMP production, degradation, and exclusion. We have previously ...
Evaluation of the primitive fraction by functional in vitro assays at the RNA and DNA level represents a novel tool for complementing molecular monitoring in chronic myeloid leukemia
(Impact Journals, 2018-04)
Quantification of BCR-ABL1 mRNA levels in peripheral blood of chronic myeloidleukemia patients is a strong indicator of response to tyrosine-kinase inhibitors (TKI)treatment. However, additional prognostic markers are ...
miRNome profiling of LSC-enriched CD34+CD38−CD26+ fraction in Ph+ CML-CP samples from Argentinean patients: a potential new pharmacogenomic tool
(Frontiers Media, 2021-01-11)
Chronic myeloid leukemia (CML) is a myeloid stem cell neoplasm characterized by an expansion of myeloid progenitor cells and the presence of BCR-ABL1 oncoprotein. Since the introduction of specific BCR-ABL1 tyrosine kinase ...
miRNome profiling of clonal stem cells in Ph+ CML
(Cold Spring Harbor Laboratory Press, 2020-03)
Chronic myeloid leukemia (CML) is a myeloid stem cell neoplasm characterized by an expansion of myeloid progenitor cells and the presence of BCR-ABL1 oncoprotein. Since the introduction of specific BCR-ABL1 tyrosine kinase ...
Infiltración cutánea por células blásticas : presentación de un casoCutaneous infiltration by blast cells : a case report
(Universidad Nacional de Cuyo. Facultad de Ciencias Médicas, 2018)
Chronic lymphocytic leukemia cells increase neutrophils survival and promote their differentiation into CD16 high CD62L dim immunosuppressive subset
(John Wiley & Sons Inc, 2019-09)
Reprogramming of neutrophils by malignant cells is well-described for many types of solid tumors, but data remain scarce for hematological diseases. Chronic lymphocytic leukemia (CLL) is characterized for a deep immune ...