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Adrenocortical response to sepsis in insulin resistant animals
(Fundación Revista Medicina, 2019)
Adrenal insufficiency in patients with insulin resistance(IR) could affect the body´s response to stressful situations. Administrationof sucrose in the drinking water (DRS), to rodents, constitutes a valid modelfor human ...
Histological demonstration of apoptosis activation in the liver fluke (Fasciola hepatica) following Closantel treatment of experimentally-infected sheep
(Fundación Revista Medicina, 2019)
The apoptosis can be by DNA damage, cytokine expression, etc. The study of apoptosis has application for the understanding of biological events, such as the tumorogenesis,the action mechanism to drugs, etc. For the apoptosis ...
Cys-loop receptors in Caenorhabditis elegans as pharmacological drug targets (Simposio)
(Fundación Revista Medicina, 2019)
The free-living nematode Caenorhabditis elegans has emerged as a powerful model for the study of the nervous system and human diseases and as a model for antiparasitic drug discovery. This nematode has also shown promise ...
Effects of prenatal stress and postnatal high fat diet feeding on BALB/c mice metabolism
(Fundación Revista Medicina, 2019)
In-utero exposure to maternal stress increases short and long term risk of suffering metabolic diseases. Exposure to stressful events leads to an increase in glucocorticoids release by activation of the HPA axis, therefore ...
20-Hydroxyeicosatetraenoic acid (20-hete) promotes a malignant phenotype in human castration-resistant prostate cancer cells through stimulation of the g protein-coupled receptor gpr75
(Fundación Revista Medicina, 2019)
20-Hydroxyeicosatetraenoic acid (20- HETE), the product of 20-hydroxylation of arachidonic acid by cytochrome P450 isoforms (CYP4F2 and CYP4A11), has a role in the oncogenesis of several human tumors. Recently, the GPR75 ...
A deficitary model of CDK5 does not impairs neuronal differentiation of human pluripotent stem cells
(Medicina, 2021)
CDK5/P35 is a complex involved in neuronal homeostasis and de- velopment that was described as a critical player for neuronal surviv- al. Besides, its deregulation is linked with neurodegenerative pathol- ogies such as ...
Anthelmintic activity of Stevia aristata extract on Echinococcus granulosus: in vitro and in vivo study
(Fundación Revista Medicina, 2021)
Cystic echinococcosis (CE) is a worldwide zoonotic disease caused by Echinococcus granulosus, which produces long-term infections in humans and animals. Available anti-parasitic treatment against CE is mostly limited to ...
A proteomic study reveals new markers of prolactin-modulated ovarian function in plains vizcachas
(Fundación Revista Medicina, 2021)
Prolactin (PRL) modulates the expression of the LH receptor in the ovary and, thus, the cascades of steroidogenic enzymes that synthesize and produce ovarian steroids. When pathological hyperprolactinemia occurs, the ...
Effect of hexachlorobenzene (hcb) and protein x of the hepatitis b virus (hbv) on liver cell growth dysregulation
(Medicina (Buenos Aires), 2021)
Chronic hepatitis B and exposure to persistent organic pollutants (POPs) can lead to cellular hepatocarcinoma (HCC), the most common liver tumor. HBV DNA encodes transactivator X (HBx). HCB is a COP promoter of hepatic ...
Protective effect of Enterococcus faecalis CECT7121 against Trichinella spiralis infection in mice
(Fundación Revista Medicina, 2019)
Trichinellosis is an important parasitic zoonosis produced by the ingestion of raw or undercooked meat infected by Trichinella spiralis larvae. At the present, the pharmacological treatment against Trichinellosis in human ...