Buscar
Mostrando ítems 71-80 de 96
Spread of clonally related escherichia coli strains harboring an IncA/C1Plasmid encoding IMP-8 and its recruitment into an unrelated MCR-1-containing isolate
(American Society for Microbiology, 2018-06)
Ten IMP-8-producing Escherichia coli isolates were recovered from surveillance cultures of a neonatal intensive care unit; eight of the isolates were clonally related. A 168.2-kb blaIMP-8 plasmid was fully sequenced, and ...
Emergence of ceftazidime/avibactam resistance in KPC-8–producing Klebsiella pneumoniae in South America
(Wiley Blackwell Publishing, Inc, 2020-09)
Klebsiella pneumoniae is one of the so-called ESKAPE pathogens. These organisms are the main cause of nosocomial infections worldwide, causing life-threatening infections amongst critically ill and immunocompromised ...
Genomic analysis of the first isolate of KPC-2-producing Klebsiella pneumoniae from Uruguay
(Elsevier, 2018-12-03)
Objectives: Since KPC-2-producing Klebsiella pneumoniae are associated with successful dissemination of a major clone, defined as sequence type 258 (ST258), the aim of this study was to perform whole-genome sequencing (WGS) ...
Baclofen prevents the elevated plus maze behavior and BDNF expression during naloxone precipitated morphine withdrawal in male and female mice
(Wiley-liss, Div John Wiley & Sons Inc, 2016-05)
In previous studies we have shown that baclofen, a selective GABAB receptor agonist, prevents the somatic expression and reestablishes the dopamine and μ-opioid receptors levels, modified during naloxone-precipitated ...
Three Novel Acinetobacter baumannii Plasmid Replicase-Homology Groups Inferred from the Analysis of a Multidrug-Resistant Clinical Strain Isolated in Argentina
(ClinMed International Library, 2017-12)
Acinetobacter baumannii is an important opportunistic pathogen responsible for a variety of nosocomial infections [1,2]. Its success in the hospital environment obeys to multiple causes, among them, the ability to resist ...
New TEM-derived extended-spectrum β-lactamase and its genomic context in plasmids from Salmonella enterica serovar derby isolates from Uruguay
(American Society for Microbiology, 2006-02)
A small (8.2-kb) ColE1 plasmid encoding TEM-144 (a new β-lactamase with a ceftazidimase profile) was sequenced by a gene-walking strategy. The blaTEM allele was carried on a Tn2 element, disrupting a Rom protein gene. ...
Molecular and biochemical characterization of CTX-M-131, a natural Asp240Gly variant derived from CTX-M-2, produced by a Providencia rettgeri clinical strain in São Paulo, Brazil
(American Society for Microbiology, 2015-03)
CTX-M-131 is a natural Asp240Gly variant from the CTX-M-2 group detected in a Providencia rettgeri clinical strain from Brazil. Molecular analysis showed that blaCTX-M-131 was inserted in a complex class 1 integron harbored ...
Metagenomic strategies identify diverse integron-integrase and antibiotic resistance genes in the Antarctic environment
(John Wiley & Sons Inc., 2021-10)
The objective of this study is to identify and analyze integrons and antibiotic resistance genes (ARGs) in samples collected from diverse sites in terrestrial Antarctica. Integrons were studied using two independent methods. ...
Bisthiazolidines: A Substrate-Mimicking Scaffold as an Inhibitor of the NDM-1 Carbapenemase
(American Chemical Society, 2016-01)
Pathogenic Gram-negative bacteria resistant to almost all β-lactam antibiotics are a major public health threat. Zn(II)-dependent or metallo-β-lactamases (MBLs) produced by these bacteria inactivate most β-lactam antibiotics, ...
Complex Class 1 Integrons with Diverse Variable Regions, Including aac(6′)-Ib-cr, and a Novel Allele, qnrB10, Associated with ISCR1 in Clinical Enterobacterial Isolates from Argentina
(American Society for Microbiology, 2007-12)
Transferable quinolone resistance has not previously been reported in Argentina. Here we describe three complex class 1 integrons harboring the novel allele qnrB10 in a unique region downstream of orf513, one of them also ...