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Mostrando ítems 61-70 de 77
Caracterización del rol de los transportadores celulares: implicancias terapéuticas en medicina veterinariaPhysio-pharmacological implications of p-glycoprotein in domestic animals
(Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias, 2005-12)
La glicoproteína-P (gp-P) es una proteína transportadora de membrana asociadaal fenómeno de resistencia a múltiples drogas (MDR). Inicialmente descripta porsu sobreexpresión en líneas celulares tumorales resistentes a ...
Cranial and endocranial diversity in extant and fossil atelids (Platyrrhini: Atelidae): A geometric morphometric study
(Veterinary and Human Toxicology, 2019-06)
Objectives: Platyrrhines constitute a diverse clade, with the modern Atelidae exhibiting the most variation in cranial and endocast morphology. The processes responsible for this diversification are not well understood. ...
NetSurfP-2.0: Improved prediction of protein structural features by integrated deep learning
(Veterinary and Human Toxicology, 2019-06-20)
The ability to predict local structural features of a protein from the primary sequence is of paramount importance for unraveling its function in absence of experimental structural information. Two main factors affect the ...
Skull diversity and evolution in miniaturized amphibians, genus Brachycephalus (Anura: Brachycephalidae)
(Veterinary and Human Toxicology, 2020-10)
Miniaturized amphibians of the genus Brachycephalus are phenotypically diverse. The species of Brachycephalus have bufoniform or leptodactyliform baupläne and any of three skeletal states: nonhyperossified, hyperossified ...
Dodecenylsuccinic anhydride modified collagen hydrogels loaded with simvastatin as skin wound dressings
(Veterinary and Human Toxicology, 2019-05)
Skin wound healing presents a unique challenge because of its complex healing process. Herein, we developed a hydrophobic wound dressing to incorporate simvastatin, which has potential application in the treatment of ulcers ...
Eco‐geographic adaptations in the human ribcage throughout a 3D geometric morphometric approach
(Veterinary and Human Toxicology, 2018-02)
Objectives: According to eco-geographic rules, humans from high latitude areas present larger and wider trunks than their low-latitude areas counterparts. This issue has been traditionally addressed on the pelvis but ...
Characterization of intellectual disability and autism comorbidity through gene panel sequencing
(Veterinary and Human Toxicology, 2019-08)
Intellectual disability (ID) and autism spectrum disorder (ASD) are clinically and genetically heterogeneous diseases. Recent whole exome sequencing studies indicated that genes associated with different neurological ...
Temporal patterns of lipoperoxidation and antioxidant enzymes are modified in the hippocampus of vitamin A-deficient rats
(Veterinary and Human Toxicology, 2009-09)
Animals can adapt their behavior to predictable temporal fluctuations in the environment through both, memory-and-learning processes and an endogenous time-keeping mechanism. Hippocampus plays a key role in memory and ...
Distribution of maternal lineages in hunter-gatherer societies of the southern coast of Tierra del Fuego, Argentina
(Veterinary and Human Toxicology, 2020-06)
Objectives: The aim of this work is to explore the maternal genetic diversity of hunter-gatherers of the southern Tierra del Fuego, specifically the north coast of Beagle Channel, the Península Mitre, and Isla de los Estados ...
Factors affecting the use of 13Cα chemical shifts to determine, refine, and validate protein structures
(Veterinary and Human Toxicology, 2008-05)
Interest centers here on the analysis of two different, but related, phenomena that affect side-chain conformations and consequently 13Cα chemical shifts and their applications to determine, refine, and validate protein ...