Buscar
Mostrando ítems 51-60 de 469
From Genome to Drugs: New Approaches in Antimicrobial Discovery
(Frontiers Media, 2021-06)
Decades of successful use of antibiotics is currently challenged by the emergence of increasingly resistant bacterial strains. Novel drugs are urgently required but, in a scenario where private investment in the development ...
GeM-Pro: a tool for genome functional mining and microbial profiling
(Springer, 2019-04)
Gem-Pro is a new tool for gene mining and functional profiling of bacteria. It initially identifies homologous genes using BLAST and then applies three filtering steps to select orthologous gene pairs. The first one uses ...
Expanding the size limit of RNA viruses: Evidence of a novel divergent nidovirus in California sea hare, with a ~35.9 kb virus genome
(BioRxiv, 2018-04-24)
While RNA viruses thrive with massive structural and functional diversity, their genomes size variation is particularly low, ranging only from ~2-to-33 kb. Here, I present the characterization of RNA sequences corresponding ...
Functional classification of plant long noncoding RNAs: a transcript is known by the company it keeps
(Wiley Blackwell Publishing, Inc, 2020-09)
The extraordinary maturation in high‐throughput sequencing technologies has revealed the existence of a complex network of transcripts in eukaryotic organisms, including thousands of long noncoding (lnc) RNAs with little ...
Yerba mate (Ilex paraguariensis, A. St.-Hil.) de novo transcriptome assembly based on tissue specific genomic expression profiles
(BioMed Central, 2018-12)
Background: The most common infusion in southern Latin-American countries is prepared with dried leaves of Ilex paraguariensis A. St.-Hil., an aboriginal ancestral beverage known for its high polyphenols concentration ...
Yerba mate (Ilex paraguariensis, A. St.-Hil.) de novo transcriptome assembly based on tissue specific genomic expression profiles
(BioMed Central, 2018-12-07)
Background: The most common infusion in southern Latin-American countries is prepared with dried leaves of Ilex paraguariensis A. St.-Hil., an aboriginal ancestral beverage known for its high polyphenols concentration ...
Identification of key microorganisms in facultative stabilization ponds from dairy industries, using metagenomics
(PeerJ Publishing, 2022-03-14)
Wastewater stabilization ponds are a natural form of wastewater treatment. Their low operation and maintenance costs have made them popular, especially in developing countries. In these systems, effluents are retained for ...
Rapid, selection-free, high-efficiency genome editing in protozoan parasites using CRISPR-cas9 ribonucleoproteins
(American Society for Microbiology, 2017-11-07)
Trypanosomatids (order Kinetoplastida), including the human pathogens Trypanosoma cruzi (agent of Chagas disease), Trypanosoma brucei, (African sleeping sickness), and Leishmania (leishmaniasis), affect millions of people ...
High-Up: A Remote Reservoir of Microbial Extremophiles in Central Andean Wetlands
(Frontiers Research Foundation, 2015-12)
The Central Andes region displays unexplored ecosystems of shallow lakes and salt flats at mean altitudes of 3700 m. Being isolated and hostile, these so-called “High-Altitude Andean Lakes” (HAAL) are pristine and have ...
Developing integrated crop knowledge networks to advance candidate gene discovery
(Elsevier, 2016-12)
The chances of raising crop productivity to enhance global food security would be greatly improved if we had a complete understanding of all the biological mechanisms that underpinned traits such as crop yield, disease ...