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Evidence of recent interspecies horizontal gene transfer regarding nucleopolyhedrovirus infection of Spodoptera frugiperda
(BioMed Central, 2015-11)
Background: Baculoviruses are insect-associated viruses carrying large, circular double-stranded-DNA genomes with significant biotechnological applications such as biological pest control, recombinant protein production, ...
Glucagon-like peptide 2 prevents down-regulation of intestinal multidrug resistance-associated protein 2 and P-glycoprotein in endotoxemic rats
(Elsevier Ireland, 2017-09)
Multidrug resistance-associated protein 2 (Mrp2, ABCC2) and P-glycoprotein (P-gp, ABCB1) constitute essential components of the intestinal biochemical barrier that prevent incorporation of food contaminants, drugs or toxic ...
The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria
(Società Italo-Latinoamericana di Etnomedicina, 2019-12)
Medicinal plants have been shown to exert a plethora of biological and pharmacological which has been associated with the presence of several bioactive components. In this study, the effects of crude extracts of Citrullus ...
Differential region-specific regulation of α4β2* nAChRs by self-administered and non-contingent nicotine in C57BL/6J mice
(Wiley Blackwell Publishing, Inc, 2010-10)
Neuronal nAChR upregulation is the hallmark of chronic nicotine exposure. Neuroplasticity to abused drugs, however, depends on whether their administration is forced by the experimenter or is under the control of the ...
Reversion of down-regulation of intestinal multidrug resistance-associated protein 2 in fructose-fed rats by geraniol and vitamin C: Potential role of inflammatory response and oxidative stress
(Elsevier Science Inc, 2019-06)
Intestinal multidrug resistance-associated protein 2 is an ABC transporter that limits the absorption of xenobiotics ingested orally, thus acting as essential component of the intestinal biochemical barrier. Metabolic ...
Reduction of the P5A-ATPase Spf1p phosphoenzyme by a Ca2+-dependent phosphatase
(Public Library of Science, 2020-04)
P5 ATPases are eukaryotic pumps important for cellular metal ion, lipid and protein homeostasis; however, their transported substrate, if any, remains to be identified. Ca2+ was proposed to act as a ligand of P5 ATPases ...
Resistance to inhibitors of cholinesterase 3 (Ric-3) expression promotes selective protein associations with the human α7-nicotinic acetylcholine receptor interactome
(Public Library of Science, 2015-08)
The α7-nicotinic acetylcholine receptor (α7-nAChR) is a ligand-gated ion channel widely expressed in vertebrates and is associated with numerous physiological functions. As transmembrane ion channels, α7-nAChRs need to be ...
Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: Physicochemical characterization and in vitro/in vivo evaluation
(Elsevier Science, 2018-07)
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) represent promising alternatives for drug delivery to the central nervous system. In the present work, four different nanoformulations of the antiepileptic ...
Soil structure and glyphosate fate under no-till manangement in the pampa region. II. Glyphosate and AMPA persistence and spatial distribution in the long-term. A conceptual model
(Elsevier, 2022-07-14)
Glyphosate and AMPA were measured in a no-tilled (NT) soil and in the runoff resulting from the rain simulation carried out after 270 days of the application of the herbicide. Glyphosate concentration was in low values in ...
Biomolecular study and conjugation of two paraaminobenzoic acid derivatives with serum proteins: drug binding efficacy and protein structural analysis.
(Adenine Press, 2020-02)
Two aminobenzoic acid derivatives DAB-0 and DAB-1 showed distinct biological properties on murine bladder cancer (BCa) cell line MB49-I. In contrast to DAB-1, DAB-0 does not possess any anti-inflammatory activity and is ...