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Persistent activation of the mammalian target of rapamycin signaling pathway in cutaneous squamous cell carcinomas in cats
(Wiley Blackwell Publishing, Inc, 2021-07)
Background: Cutaneous squamous cell carcinoma (CSCC) represents the most common malignant tumour of the feline skin. Emerging evidence suggests that the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin ...
Stress-regulated elements in Lotus spp., as a possible starting point to understand signalling networks and stress adaptation in legumes
(PeerJ Inc., 2021-08)
Although legumes are of primary economic importance for human and livestock consumption, the information regarding signalling networks during plant stress response in this group is very scarce. Lotus japonicus is a major ...
Cross-talk between mitochondrial function, growth, and stress signalling pathways in plants
(Oxford University Press, 2020-12)
Plant mitochondria harbour complex metabolic routes that are interconnected with those of other cell compartments and changes in mitochondrial function remotely influence processes in different parts of the cell. This ...
New insights into the control of neurotrophic growth factor receptor signaling: Implications for nervous system development and repair
(Wiley Blackwell Publishing, Inc, 2012-12)
Neurotrophic growth factors control neuronal development by activating specific receptor tyrosine kinase positive signaling pathways, such as Ras-MAPK and PI3K-Akt cascades. Once activated, neurotrophic factor receptors ...
Sucrose signaling in plants: A world yet to be explored
(Taylor & Francis, 2013-03)
The role of sucrose as a signaling molecule in plants was originally proposed several decades ago. However, recognition of sucrose as a true signal has been largely debated and only recently this role has been fully accepted. ...
A highly efficient modified human serum albumin signal peptide to secrete proteins in cells derived from different mammalian species
(Academic Press Inc Elsevier Science, 2017-04)
Signal peptides (SPs) are key elements in the production of recombinant proteins; however, little information is available concerning different SP in mammalian cells other than CHO. In order to study the efficiency of ...
Light and temperature cues: multitasking receptors and transcriptional integrators.
(Wiley Blackwell Publishing, Inc, 2018-02)
The combined information provided by light and temperature cues helps to optimise plant body architecture and physiology. Plants possess elaborate systems to sense and respond to these stimuli. Simultaneous perception of ...
Integration of Plasma Membrane and Nuclear Signaling in Elicitor Regulation of Plant Secondary Metabolism
(Natural Products, 2008-08-01)
The plant kingdom represents a valuable source of natural products of commercial interest. These compounds, named secondary metabolites, are not essential for the survival of plants, but confer them some advantages that ...
Estrogen receptors and signaling pathways in lactotropes and somatotropes
(Karger, 2010-12)
Estrogens are crucial determinants in the regulation of anterior pituitary function and maintenance of tissue homeostasis. Estrogen actions in this gland are exerted through both classical and non-classical mechanisms of ...
Interspecific territoriality despite vocal divergence in two sympatric Laterallus crakes
(Springer, 2020-04-26)
Territoriality is a widespread behavioral phenomenon that functions for partitioning space and defending resources. Birds tend to defend territories against homospecific individuals through long-distance acoustic signals, ...