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Down-regulation of NF-κB signaling by Gordonia bronchialis prevents the activation of gut epithelial cells
(Sage Publications Ltd, 2014-08)
The immunomodulatory power of heat-killed Gordonia bronchialis was studied on gut epithelial cells activated with pro-inflammatory stimuli (flagellin, TNF-α or IL-1β). Light emission of luciferase-transfected epithelial ...
Labile iron pool and ferritin content in developing rat brain γ-irradiated in utero
(Elsevier Science, 2009-05)
This study was aimed to assess the content of total Fe, Ferritin (Ft) and labile Fe pool (LIP) in developing rat brain exposed in utero to 1 Gy of gamma irradiation. A significant increase (2.3-fold) in the total Fe content ...
Evaluation of the chagas western blot igg assay for the diagnosis of chagas disease
(MDPI, 2021-11-10)
Chagas disease is a debilitating and often fatal pathology resulting from infection by the protozoan parasite Trypanosoma cruzi. In its recommendations, the World Health Organization states that the diagnosis of T. cruzi ...
Cross-reactivity between the soybean protein P34 and bovine caseins
(Korean Academy of Asthma, Allergy and Clinical Immunology, 2015-01)
Purpose: Soy-based formulas are widely used as dairy substitutes to treat milk allergy patients. However, reactions to soy have been reported in a small proportion of patients with IgE-mediated milk allergies. The aim of ...
Rapid nongenomic effects of 3,5,3′-triiodo-L-thyronine on the intracellular pH of L-6 myoblasts are mediated by intracellular calcium mobilization and kinase pathways
(Endocrine Society, 2004-12)
L-T3 and L-T4 activated the Na+/H + exchanger of L-6 myoblasts, with a fast nongenomic mechanism, both in the steady state and when cells undergo acid loading with ammonium chloride. Monitored with the intracellular ...
Adenoviral transfer of human aquaporin-1 gene to rat liver improves bile flow in estrogen-induced cholestasis
(Nature Publishing Group, 2014-08)
Estrogens can cause liver cholestatic disease. As downregulation of hepatocyte canalicular aquaporin-8 (AQP8) water channels has been involved in estrogen-induced bile secretory failure, we tested whether the archetypal ...
Role of PTHrP in human intestinal Caco-2 cell response to oxidative stress
(Elsevier, 2013-07)
We have previously demonstrated that parathyroid hormone (PTH) induces apoptosis in human colon adenocarcinoma Caco-2 cells but the effects of its tumoral analog PTH-related peptide (PTHrP) in this cell line are still ...
Atrial natriuretic peptide attenuates endoplasmic reticulum stress in experimental acute pancreatitis
(Elsevier Science, 2019-02)
Increasing evidence shows that the endoplasmic reticulum (ER) stress is an early event that injures pancreatic acinar cells and contributes to the pathogenesis of acute pancreatitis. In the present work we sought to establish ...
Relationship between the dimerization of thyroglobulin and its ability to form triiodothyronine
(American Society for Biochemistry and Molecular Biology, 2018-03)
Thyroglobulin (TG) is the most abundant thyroid gland protein, a dimeric iodoglycoprotein (660 kDa). TG serves as the protein precursor in the synthesis of thyroid hormones tetraio-dothyronine (T 4 ) and triiodothyronine ...
Retinoic acid induces nuclear FAK translocation and reduces breast cancer cell adhesion through Moesin, FAK, and Paxillin
(Elsevier Ireland, 2016-07-15)
Breast cancer is the most common malignancy in women, with metastases being the cause of death in 98%. In previous works we have demonstrated that retinoic acid (RA), the main retinoic acid receptor (RAR) ligand, is involved ...