Buscar
Mostrando ítems 31-40 de 243
Amyloid-beta neurotoxicity and clearance are both regulated by glial group II metabotropic glutamate receptors
(Pergamon-Elsevier Science Ltd, 2017-09)
Astrocytes are now fully endorsed as key players in CNS functionality and plasticity. We recently showed that metabotropic glutamate receptor 3 (mGlu3R) activation by LY379268 promotes non-amyloidogenic cleavage of amyloid ...
Low arsenic concentrations impair memory in rat offpring exposed during pregnancy and lactation: Role of α7 nicotinic receptor, glutamate and oxidative stress
(Elsevier Science, 2018-07)
Inorganic arsenic (iAs) is an important natural pollutant. Millions of individuals worldwide drink water with high levels of iAs. Arsenic exposure has been associated to cognitive deficits. However, the underlying mechanisms ...
Optimization of batch culture conditions for GABA production by Lactobacillus brevis CRL 1942, isolated from quinoa sourdough
(Elsevier, 2016-04)
ƴ-aminobutyric acid (GABA) is a four-carbon amino acid, that acts as a major inhibitory neurotransmitter in the central nervous system. Among nineteen lactic acid bacteria strains, isolated from Andean amaranth (A) and ...
Differental effects of glatamate agonist and D-aspartate on oxytocin release from hypothalamus and posterior pituitary of male rats.
(Humana Press, 2001-12)
In order to determine whether ionotropic (iGluRs) and metabotropic (mGluRs) glutamate receptor activation modulates oxytocin release in male rats, we investigated the effect of agonists of both types of glutamate receptors ...
Adaptive changes in the rat hippocampal glutamatergic neurotransmission are observed during long-term treatment with lorazepam
(Springer, 2003-12)
Rationale: Chronic treatment with benzodiazepines induces tolerance to most of their pharmacological effects. The best-studied neurochemical correlation to this phenomenon involves GABAergic adaptive changes. However, some ...
Basal forebrain cholinergic system and memory
(Springer, 2018-03)
Basal forebrain cholinergic neurons constitute a way station for many ascending and descending pathways. These cholinergic neurons have a role in eliciting cortical activation and arousal. It is well established that they ...
Cross-sensitization between cocaine and acute restraint stress is associated with sensitized dopamine but not glutamate release in the nucleus accumbens
(Wiley Blackwell Publishing, Inc, 2013-03)
Repeated administration of psychostimulant drugs or stress can elicit a sensitized response to the stimulating and reinforcing properties of the drug. Here we explore the mechanisms in the nucleus accumbens (NAc) whereby ...
FSH and bFGF stimulate the production of glutathione in cultured rat sertoli cells
(Wiley Blackwell Publishing, Inc, 2009-06)
Migration of developing germ cells from the basal to the adluminal compartment of the seminiferous epithelium requires extensive tissue restructuring, resulting in the production of reactive oxygen species. Sertoli cells ...