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AmpuBase: A transcriptome database for eight species of apple snails (Gastropoda: Ampullariidae)
(BioMed Central, 2018-03)
Gastropoda, with approximately 80,000 living species, is the largest class of Mollusca. Among gastropods, apple snails (family Ampullariidae) are globally distributed in tropical and subtropical freshwater ecosystems and ...
Liver mitochondrial DNA damage and genetic variability of Cytochrome b – a key component of the respirasome – drive the severity of fatty liver disease
(Wiley Blackwell Publishing, Inc, 2020-07-07)
Background and aims: The progression of nonalcoholic fatty liver disease (NAFLD) into severe histological forms (steatohepatitis – NASH) is paralleled by the occurrence of complex molecular processes. Mitochondrial dysfunction ...
Comparative transcriptome analysis of geographically distinct virulent and attenuated Babesia bovis strains reveals similar gene expression changes through attenuation
(2013-11)
Background: Loss of virulence is a phenotypic adaptation commonly seen in prokaryotic and eukaryotic pathogens. This mechanism is not well studied, especially in organisms with multiple host and life cycle stages such as ...
Deciphering the transcriptomic regulation of heat stress responses in Nothofagus pumilio
(Plos One, 2021-03-30)
Global warming is predicted to exert negative impacts on plant growth due to the damaging effect of high temperatures on plant physiology. Revealing the genetic architecture underlying the heat stress response is therefore ...
Molecular basis of a bacterial-amphibian symbiosis revealed by comparative genomics, modeling, and functional testing
(Nature Publishing Group, 2021-10)
The molecular bases for the symbiosis of the amphibian skin microbiome with its host are poorly understood. Here, we used the odor-producer Pseudomonas sp. MPFS and the treefrog Boana prasina as a model to explore bacterial ...
Immunobiotic Lactobacillus jensenii TL2937 Alleviates Dextran Sodium Sulfate-Induced Colitis by Differentially Modulating the Transcriptomic Response of Intestinal Epithelial Cells
(Frontiers Media S.A., 2020-09-17)
Immunobiotics have emerged as a promising intervention to alleviate intestinal damage in inflammatory bowel disease (IBD). However, the beneficial properties of immunobiotics are strain dependent and, therefore, each strain ...
Transcriptomic analysis and molecular docking reveal genes involved in the response of Aedes aegypti larvae to an essential oil extracted from Eucalyptus
(Public Library of Science, 2021-07)
Background: Aedes aegypti (L.) is an urban mosquito, vector of several arboviruses that cause severe diseases in hundreds of million people each year. The resistance to synthetic insecticides developed by Ae. aegypti ...
Distinct properties of layer 3 pyramidal neurons from prefrontal and parietal areas of the monkey neocortex
(Society for Neuroscience, 2019-07)
In primates, working memory function depends on activity in a distributed network of cortical areas that display different patterns of delay task-related activity. These differences are correlated with, and might depend ...
A cluster of MYB transcription factors regulates anthocyanin biosynthesis in carrot (Daucus carota L.) root and petiole
(Frontiers Media S.A., 2019-01-14)
Purple carrots can accumulate large quantities of anthocyanins in their roots and – in some genetic backgrounds-petioles, and therefore they represent an excellent dietary source of antioxidant phytonutrients. In a previous ...
Comprehensive transcriptomic analysis of heat shock proteins in the molecular subtypes of human breast cancer
(BioMed Central, 2018-06)
Background: Heat Shock Proteins (HSPs), a family of genes with key roles in proteostasis, have been extensively associated with cancer behaviour. However, the HSP family is quite large and many of its members have not been ...