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The interplanetary magnetic structure that guides solar relativistic particles
(EDP Sciences, 2012-01)
Context. Relating in-situ measurements of relativistic solar particles to their parent activity in the corona requires understanding the magnetic structures that guide them from their acceleration site to the Earth. ...
Preparation of TPP-crosslinked chitosan microparticles by spray drying for the controlled delivery of progesterone intended for estrus synchronization in cattle
(Springer/Plenum Publishers, 2018-03)
Purpose: Planned reproduction in cattle involves regulation of estrous cycle and the use of artificial insemination. Cycle control includes the administration of exogenous progesterone during 5–8 days in a controlled manner ...
Magnetized hybrid stars: Effects of slow and rapid phase transitions at the quark-hadron interface
(Wiley Blackwell Publishing, Inc, 2019-11)
We study the influence of strong magnetic fields in hybrid stars, composed by hadrons and a pure quark matter core, and analyse their structure and stability as well as some possible evolution channels due to the magnetic ...
Intracellular cyclic AMP levels modulate differential adaptive responses on epimastigotes and cell culture trypomastigotes of Trypanosoma cruzi
(Elsevier Science, 2020-02)
Among the many environmental challenges the parasiteTrypanosoma cruzihas to overcome to complete its lifecycle through different hosts, oxidative stress plays a central role. Different stages of this parasite encounterdistinct ...
A highly concentrated and taste-improved aqueous formulation of efavirenz for a more appropriate pediatric management of the anti-HIV therapy
(Bentham Science Publishers, 2010-04)
Pediatric HIV is scarce in developed countries; 90% of pediatric HIV patients are in developing countries. In contrast, children represent 15% of the new infections in poor countries. Approximately 90% of the HIV-positive ...
The chemically-modified tetracycline COL-3 and its parent compound doxycycline prevent microglial inflammatory responses by reducing glucose-mediated oxidative stress
(MDPI, 2021-08-22)
We used mouse microglial cells in culture activated by lipopolysaccharide (LPS) or α-synuclein amyloid aggregates (αSa) to study the anti-inflammatory effects of COL-3, a tetracycline derivative without antimicrobial ...
Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates
(Multidisciplinary Digital Publishing Institute, 2019)
Abstract: Aggregated forms of the synaptic protein α‐synuclein (αS) have been proposed to operateas a molecular trigger for microglial inflammatory processes and neurodegeneration in Parkinson´sdisease. Here, we used brain ...
Effects of 22 Ne sedimentation and metallicity on the local 40 pc white dwarf luminosity function
(EDP Sciences, 2019-08-06)
Aims: We analyzed the effect of the sedimentation of 22Ne on the local white dwarf luminosity function by studying scenarios under different Galactic metallicity models. Methods: We use an advanced population synthesis ...