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Electron capture by swift ions from molecules of biological interest
(IOP Publishing, 2018-07)
Electron capture from molecular targets impacted by swift ions, H+, He2+, Li3+ and C6+, is investigated in the framework of the quantum-mechanical continuum distorted wave-Eikonal initial state model. Biological molecules ...
CleanBSequences: an efficient curator of biological sequences in R
(Springer Heidelberg, 2020-04)
This work presents a new method and tool to solve a common problem of molecular biologists and geneticists who use molecular markers in their scientific research and developments: curation of sequences. Omic studies conducted ...
LAMP technology: Rapid identification of Brucella and Mycobacterium avium subsp. paratuberculosis
(Sociedade Brasileira de Microbiologia, 2015-06)
In this study, we developed new sets of primers to detect Brucella spp. and M. avium subsp. paratuberculosis (MAP) through isothermal amplification. We selected a previously well-characterized target gene, bscp31, specific ...
A closed-tube loop-mediated isothermal amplification assay for the visual endpoint detection of Brucella spp. and Mycobacterium avium subsp. paratuberculosis
(Springer, 2017-06)
LAMP (loop-mediated isothermal amplification) is an isothermal nucleic acid amplification technique that is characterized by its efficiency, rapidity, high yield of final product, robustness, sensitivity, and specificity, ...
Microwave-assisted synthesis, biological assessment, and molecular modeling of aza-heterocycles: Potential inhibitory capacity of cholinergic enzymes to Alzheimer's disease
(Elsevier Science, 2021-01-15)
A highly regioselective solvent-free microwave-assisted synthesis of pyrazoles and tetrahydroindazoles based on the condensation of 1,3-diketones with arylhydrazines is described. Compounds were evaluated as cholinesterase ...
When the Cell Stress Society International became South American: meeting report of the IX International Workshop on the Molecular Biology of Stress Responses
(Springer, 2013-01)
The International Workshop on the Molecular Biology of the Stress Response organized by the Cell Stress Society International was held in Porto Alegre, Brazil, on May 27–30, 2012, as part of the development of the Latin ...
Pan-cancer molecular patterns and biological implications associated with a tumor-specific molecular signature
(Multidisciplinary Digital Publishing Institute, 2021-01)
Studying tissue-independent components of cancer and defining pan-cancer subtypes could be addressed using tissue-specific molecular signatures if classification errors are controlled. Since PAM50 is a well-known, United ...
Understanding new molecular and cell biology findings based on progressive scientific practices and interconnected activities in undergraduate students
(John Wiley & Sons Inc, 2021-03)
Nowadays Molecular Cell Biology (MCB) must be taught as science is practiced. Even though there are several approaches based on scientific practices, a key aspect is to define the purpose of each of these teaching strategies ...
The Sarkarian proposal and molecular-genetic reductionismLa propuesta sarkariana y el reduccionismo genético-molecular
(Universidade Federal de Santa Catarina. Núcleo de Epistemologia e Lógica, 2021-12)
One of the most interesting and influential proposals on the subject of reductionism in Biology has been presented by Sahotra Sarkar, mainly in his book Genetics and Reductionism. There the author proposes a general model ...
Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents
(Elsevier, 2018-11)
Synthesis and biological evaluation of a novel library of fused 1,2,3-triazole derivatives are described. The in-house developed multicomponent reaction based on commercially available starting materials was applied and ...