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Leptin stimulates protein synthesis-activating translation machinery in human trophoblastic cells
(Society for the Study of Reproduction, 2009-06)
Leptin was originally considered as an adipocyte-derived signaling molecule for the central control of metabolism. However, pleiotropic effects of leptin have been identified in reproduction and pregnancy, particularly in ...
MAP kinases p38 and JNK are activated by the steroid hormone 1α,25(OH)2-vitamin D3 in the C2C12 muscle cell line
(Wiley-liss, Div John Wiley & Sons Inc, 2006-03-07)
In chick skeletal muscle cell primary cultures, we previously demonstrated that 1α,25(OH)2-vitamin D3 [1α,25(OH) 2D3], the hormonally active form of vitamin D, increases the phosphorylation and activity of the extracellular ...
Diurnal dependence of growth responses to shade in Arabidopsis: role of hormone, clock, and light signaling
(Elsevier, 2012-05)
We investigated the diurnal dependence of the hypocotyl-growth responses to shade under sunlight–night cycles in Arabidopsis thaliana. Afternoon shade events promoted hypocotyl growth, while morning shade was ineffective. ...
Dehydroepiandrosterone (DHEA) modulates GHRH, somatostatin and angiotensin II action at the pituitary level
(BioScientifica, 2005-04-01)
In view of the present controversy related to the potential beneficial effects of clinical dehydroepiandrosterone (DHEA) treatments, and considering our own previous results that reveal an influence of this steroid in ...
Role of 17b-estradiol and testosterone in apoptosis.
(Elsevier Inc, 2011-11)
17β-Estradiol (E2) and Testosterone (T) exert actions in most animal tissues, in addition to the reproductive system. Thus, both sex steroid hormones affect growth and different cell functions in several organs. Accordingly, ...
Comparing the role of anti-Müllerian hormone as a marker of FSH action in male and female fertility
(Taylor & Francis, 2019-03)
Introduction: Originally limited to the assessment of patients with congenital disorders of sexdevelopment, anti-Müllerian hormone (AMH) measurement has more recently been extended toseveral conditions affecting the ...
Genetic Mutations in the GH/IGF Axis
(Medical Media, 2018-09)
The GH/IGF axis plays an important role in the control of pre and postnatal growth. At least 48 monogenic defects have been described affecting the production, secretion, and action of GH and IGFs. Molecular defects of the ...
The direct action of estrone on vascular tissue involves genomic and non-genomic actions
(Pergamon-Elsevier Science Ltd, 2008-01)
A two step model mechanism of steroid action has been recently postulated. In this study, we test the hypothesis that, the biochemical action of estrone (E1) on vascular tissue could be performed via genomic and non-genomic ...
Male Central Hypogonadism in Paediatrics - the Relevance of Follicle-stimulating Hormone and Sertoli Cell Markers
(Touch Medical Media, 2018-09)
The definition of male hypogonadism used in adult endocrinology is not fully applicable to paediatrics. A clear understanding of the developmental physiology of the hypothalamic-pituitary-testicular axis is essential for ...
Alpha-melanocyte-stimulating hormone through melanocortin-4 receptor inhibits nitric oxide synthase and cyclooxygenase expression in the hypothalamus of male rats
(Karger, 2004-12)
There is evidence that α-melanocyte-stimulating hormone (α-MSH) has immunomodulatory and anti-inflammatory actions within the brain. In this study, we tested whether these actions are due to inhibition of the synthesis of ...