Buscar
Mostrando ítems 21-30 de 116
A transcriptomics model of estrogen action in the ovine fetal hypothalamus: evidence for estrogenic effects of ICI 182,780
(The Physiological Society, 2018-09)
Estradiol plays a critical role in stimulating the fetal hypothalamus?pituitary?adrenal axis at the end of gestation. Estradiol action is mediated through nuclear and membrane receptors that can be modulated by ICI 182,780, ...
On how to identify a seminal fluid protein : a response to Wigby et al.
(Wiley, 2022-08)
The choice of criteria to delimit a group or class is a subjective matter, even though the reasoning,
the objectives, and the criteria themselves should always be clearly stated. This paper is part of a
discussion about ...
Evidence for shared molecular pathways of dysregulated decidualization in preeclampsia and endometrial disorders revealed by microarray data integration
(Federation of American Societies for Experimental Biology, 2019-11)
Microarray data of chorionic villous samples (CVSs) obtained from women of ~11.5 gestational weeks who developed preeclampsia with severe features (sPE; PE-CVS) revealed a molecular signature of impaired endometrial ...
Transcriptomic, proteomic and metabolomic analysis of maize responses to UV-B: comparison of greenhouse and field growth conditions
(Landes Bioscience, 2011-08)
UV-B radiation from normal solar fluence elicits physiological and developmental changes in plants under fluctuating environmental conditions. Most UV photobiology studies in plants utilize controlled greenhouse and growth ...
SARS-CoV-2 Infection Boosts MX1 Antiviral Effector in COVID-19 Patients
(Elsevier, 2020-10)
In a published case-control study (GSE152075) from SARS-CoV-2-positive (n = 403) and -negative patients (n = 50), we analyzed the response to infection assessing gene expression of host cell receptors and antiviral proteins. ...
Deciphering the transcriptomic regulation of heat stress responses in Nothofagus pumilio
(Public Library of Science, 2021-03)
Global warming is predicted to exert negative impacts on plant growth due to the damaging effect of high temperatures on plant physiology. Revealing the genetic architecture underlying the heat stress response is therefore ...
Functional annotation and distribution overview of RNA families in 27 Streptococcus agalactiae genomes
(BioMed Central, 2018-07)
Background: Streptococcus agalactiae, also known as Group B Streptococcus (GBS), is a Gram-positive bacterium that colonizes the gastrointestinal and genitourinary tract of humans. This bacterium has also been isolated ...
Evidencing a pancreatic ductal adenocarcinoma subpopulation sensitive to the proteasome inhibitor Carfilzomib
(American Association for Cancer Research, 2020-10)
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with a survival rate less than 5%. Multiple chemotherapeutic drugs have been tested to improve patient prognosis; however, the clinical efficacy of these ...
Unraveling the impact on agronomic traits of the genetic architecture underlying plant-density responses in canola
(Oxford University Press, 2021-07-28)
Plant density defines vegetative architecture and the competition for light between individuals. Brassica napus (canola, rapeseed) presents a radically different plant architecture compared to traditional crops commonly ...
Squamousness gain defines pancreatic ductal adenocarcinoma hepatic metastases phenotype, and gemcitabine response
(Elsevier, 2021-09)
Background: Pancreatic ductal adenocarcinoma (PDAC) is a dismal disease with a survival rate of less than 7%, mainly due to the hepatic metastatic spread. Despite the importance of understanding PDAC metastases, central ...