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Brain circuits mediating the orexigenic action of peripheral ghrelin: Narrow gates for a vast kingdom
(Frontiers Research Foundation, 2015-03)
The nervous and endocrine systems act together to regulate all physiological processes essential for the body homeostasis control. Given the strict communication restrictions that the brain-blood barrier (BBB) imposes, the ...
Dissecting thyroid hormone transport and metabolism in dendritic cells
(BioScientifica, 2017-02)
We reported thyroid hormone (TH) receptor expression in murine dendritic cells (DCs) and 3,5,3'-triiodothyronine (T3)-dependent stimulation of DC maturation and ability to develop a Th1-type adaptive response. Moreover, ...
The intriguing ligand-dependent and ligand-independent actions of the growth hormone secretagogue receptor on reward-related behaviors
(Elsevier, 2020-01)
The growth hormone secretagogue receptor (GHSR) is a G-protein coupled receptor (GPCR) highly expressed in the brain, and also in some peripheral tissues. GHSR activity is evoked by the stomach-derived peptide hormone ...
Transferrin and thyroid hormone converge in the control of myelinogenesis
(Academic Press Inc Elsevier Science, 2015-03)
Myelination is a concerted mechanism tightly regulated in the brain. Although several factors are known to participate during this process, the complete sequence of events is far from being fully elucidated. Separate effects ...
Inhibitory pathways and the inhibition of luteinizing hormone-releasing hormone release by alcohol
(National Academy of Sciences, 2000-02)
In this research we examined the mechanisms by which ethanol (EtOH) inhibits luteinizing hormone-releasing hormone (LHRH) release from incubated medial basal hypothalamic explants. EtOH (100 mM) stimulated the release of ...
Progesterone and progestins: neuroprotection and myelin repair
(Elsevier, 2008-12)
Progesterone, known for its role in pregnancy, also exerts marked effects on the nervous system. Its neuroprotective and promyelinating actions, now well documented by experimental studies, make it a particularly promising ...
The importance of follicle-stimulating hormone in the prepubertal and pubertal testis
(Elsevier, 2020-10)
Although the attention of testis function in puberty and adulthood has been focalized in the luteinizing hormone–testosterone axis, follicle-stimulating hormone (FSH) also exerts a fundamental role in the physiology of the ...
Snakin-1 affects reactive oxygen species and ascorbic acid levels and hormone balance in potato
(PLOS, 2019-03-25)
Snakin-1 is a member of the Solanum tuberosum Snakin/GASA family. We previously demonstrated that Snakin-1 is involved in plant defense to pathogens as well as in plant growth and development, but its mechanism of action ...
Insulin enhances leptin expression in human trophoblastic cells
(Oxford University Press, 2013-06)
Leptin, one of the adipokines that controls energy metabolism via the central nervous system, also has pleiotropic peripheral effects, acting as a proinflammatory cytokine. Leptin is also produced by trophoblastic cells ...
Signal transduction pathways involved in non-genomic action of estrone on vascular tissue
(Elsevier Science Inc, 2006-10)
Previously we demonstrated that estrone non-genomically regulates rat aortic NOS and COX activity and that this effect depends on ovarian activity. The purpose of the present study was to characterize this effect and ...