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Stable graphene oxide-gold nanoparticle platforms for biosensing applications
(Royal Society of Chemistry, 2017-12)
Graphene oxide-gold nanoparticle (AuNPs@GO) hybrids were fabricated in water dispersions of graphene oxide (GO) and Au precursor completely free of stabilizing agents by UV-light irradiation. Gold nanoparticle (AuNP) ...
cDNA isolation and expression of nicotinamide adenine dinucleotide phosphate-dependent cytochrome P450 reductase gene in the chagas disease vector triatoma infestans
(American Society of Tropical Medicine and Hygiene, 2018-03)
Pyrethroid resistance has been detected in Triatoma infestans (Hemiptera: Reduviidae), which was atributed to target site insensitivity and increased oxidative metabolism of the insecticide by cytochrome P450s. Nicotinamide ...
Enhancement of Photophysical and Photosensitizing properties of Flavin Adenine Dinucleotide by Mutagenesis of the C-terminal extension of a bacterial Flavodoxin Reductase
(Wiley Vch Verlag, 2015-03)
The role of the mobile C-terminal extension present in Rhodobacter capsulatus ferredoxin–NADP(H) reductase (RcFPR) was evaluated using steady-state and dynamic spectroscopies for both intrinsic Trp and FAD in a series of ...
On the interaction of sustrate analogues with non-phosphorylating glyceraldehydes-3-phosphate dehydrogenase from celery leaves
(Elsevier Ireland, 2002-01)
Structural analogues of D-glyceraldehyde-3-phosphate (D-Ga3P) and NADP+ were studied as potential substrates and inhibitors of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.9; GAPN) from Apium ...
Amperometric detection of D-sorbitol with NAD+-D-sorbitol dehydrogenase modified carbon paste electrode
(Elsevier Science, 2000-11)
A biosensor based on modified carbon paste electrodes for the amperometric detection of D-sorbitol is described. Carbon paste electrodes were modified by D-sorbitol dehydrogenase (SDH) and nicotinamide adenine dinucleotide ...
Fabrication of a novel impedimetric biosensor for label free detection of DNA damage induced by doxorubicin
(Elsevier Science, 2019-02)
In this work, a novel impedimetric biosensor has been fabricated for detection of DNA damage induced by doxorubicin (DX). Cytochrome P450 reductase (CPR) is required for electron transfer from nicotinamide adenine dinucleotide ...
Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica
(Springer, 2011-10)
A study has been carried out to investigate whether the action of triclabendazole (TCBZ) against Fasciola hepatica is altered by inhibition of drug metabolism. The cytochrome P450 (CYP 450) enzyme pathway was inhibited ...
Parenteral succinate reduces systemic ROS production in septic rats, but it does not reduce creatinine levels
(Landes Bioscience, 2018-11)
In sepsis, reactive oxygen species (ROS) production is increased. This process takes place mainly within the electron transport chain. ROS production is part of the pathophysiology of multiple organ failure in sepsis. ...
Tetrazolium salts and formazan products in Cell Biology: Viability assessment, fluorescence imaging, and labeling perspectives
(Elsevier Gmbh, Urban & Fischer Verlag, 2018-04)
For many years various tetrazolium salts and their formazan products have been employed in histochemistry and for assessing cell viability. For the latter application, the most widely used are 3-(4,5-dimethyl-2-thiazolyl ...
Potentiation of triclabendazole sulphoxide-induced tegumental disruption by methimazole in a triclabendazole-resistant isolate of Fasciola hepatica
(Springer, 2010-05)
A study has been carried out to investigate whether the action of triclabendazole (TCBZ) against Fasciola hepatica is altered by inhibition of drug metabolism. The flavin monooxygenase system (FMO) was inhibited using ...