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Zinc(II) phthalocyanines as photosensitizers for antitumor photodynamic therapy
(Pergamon-Elsevier Science Ltd, 2019-09)
Photodynamic therapy (PDT) is a highly specific and clinically approved method for cancer treatment in which a nontoxic drug known as photosensitizer (PS) is administered to a patient. After selective tumor irradiation, ...
Interpersonal cognitions as a mechanism of change in cognitive behavioral therapy for generalized anxiety disorder?: A multilevel dynamic structural equation model approach
(American Psychological Association, 2021-11)
Objective: This study aimed to investigate the effects of changes in interpersonal cognitions on outcome during cognitive behavioral therapy (CBT) for generalized anxiety disorder (GAD) and how these effects are moderated ...
Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy
(Elsevier Science, 2009-04)
The use of endogenous protoporphyrin IX (PpIX) after administration of 5-aminolaevulinic acid (ALA) has led to many applications in photodynamic therapy (PDT). However the efficacy of ALA-PDT is sub-optimal for thicker ...
Effectiveness of ZnPc and of an amine derivative to inactivate Glioblastoma cells by Photodynamic Therapy: An in vitro comparative study
(Nature Publishing Group, 2019-12)
Glioblastoma multiforme is considered to be one of the most aggressive types of tumors of the central nervous system, with a poor prognosis and short survival periods of ~ one year. The current protocol for glioblastoma ...
Kohonen classification applying 'missing variables' criterion to evaluate the p-boronophenylalanine human-body-concentration decreasing profile of boron neutron capture therapy patients
(John Wiley & Sons Ltd, 2011-06)
The irradiation dose in tumor and healthy tissue of a boron neutron capture therapy (BNCT) patient depends on the boron concentration in blood. In most treatments, this concentration is experimentally determined before and ...
The current therapeutic options for Crohn’s disease: from medical therapy to intestinal transplantation
(Taylor & Francis, 2017-12)
Introduction: Crohn’s disease (CD) has an annual incidence per 100.000 person-year of 20.2 in North America and 12.7 in Europe, and the purpose of this review is to evaluate its medical management, from diagnosis to ...
Local application of low level laser therapy in mice ameliorates ovarian damage induced by cyclophosphamide
(Elsevier Ireland, 2021-07-01)
The aim of the present study is to assess whether low level laser therapy (LLLT) can protect ovaries from chemotherapy-induced gonadotoxicity using a mice model of premature ovarian failure induced by cyclophosphamide ...
Photothermal therapy with silver nanoplates in HeLa cells studied by: In situ fluorescence microscopy
(Royal Society of Chemistry, 2021-04)
Photothermal therapy (PTT) is a noninvasive treatment for cancer relying on the incorporation of NIR-light absorbing nanomaterials into cells, which upon illumination release heat causing thermally induced cell death. We ...
Developing strategies to predict photodynamic therapy outcome: the role of melanoma microenvironment
(Springer, 2015-12)
Melanoma is among the most aggressive and treatment-resistant human skin cancer. Photodynamic therapy (PDT), a minimally invasive therapeutic modality, is a promising approach to treating melanoma. It combines a non-toxic ...
Efficiency of antimicrobial photodynamic therapy with photodithazine® on mssa and mrsa strains
(Multidisciplinary Digital Publishing Institute, 2021-07)
Staphylococccus aureus is a ubiquitous and opportunistic bacteria associated with high mortality rates. Antimicrobial photodynamic therapy (aPDT) is based on the application of a light source and a photosensitizer that can ...