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Pharmacology and toxicology of polyphenols with potential as neurotropic agents in non-communicable diseases
(Bentham Science Publishers, 2018-03)
The central nervous system (CNS) is involved in organic integration. Nervousmodulation via bioactive compounds can modify metabolism in order to prevent systemic noncommunicablediseases (NCDs). Concerning this, plant ...
Biopharmaceutical Characteristics of Nifurtimox Tablets for Age- and Body Weight-Adjusted Dosing in Patients With Chagas Disease
(Blackwell Publishing, 2020-10)
Treatment of Chagas disease with nifurtimox requires age- and body weight-adjusted dosing, resulting in complex dosing instructions. Appropriate formulations are needed for precise and compliant dosing, especially in ...
Contaminación de los suelos afectados por el vertido de Aznalcóllar y su evolución en el tiempo (1998 - 2001)
(Sociedad Española de la Ciencia del Suelo, 2003-04)
Se ha estudiado la contaminación de los suelos afectados por el vertido minero de Aznalcóllar (As, Zn, Cd, Cu y Pb) entre Julio de 1998 y Diciembre de 2001, tanto en lo referente a contenidos totales, como a elementos ...
Anti-tuberculosis site-specific oral delivery system that enhances rifampicin bioavailability in a fixed-dose combination with isoniazid
(Springer, 2020-09-08)
The in vivo release segregation of rifampicin (RIF) and isoniazid (INH) has been proposed as a strategy to avoid RIF acid degradation, which is known as one of the main factors for reduced RIF bioavailability and can result ...
Chronic toxicity, bioavailability and bioaccumulation of Zn, Cu and Pb in Lactuca sativa exposed to waste from an abandoned gold mine
(Elsevier, 2022-11)
Abandoned mines with untreated waste cause environmental pollution. The complex mixture of mining waste includes high metal content, anthropogenic chemicals and sterile rocks. Adverse effects of contaminated soils have ...
Phytoextraction of Cu, Cd, Zn and As in four shrubs and trees growing on soil contaminated with mining waste
(Elsevier, 2022-12)
Mining activity has degraded large extensions of soil and its waste is composed of metals, anthropogenic chemicals, and sterile rocks. The use of native species in the recovery of polluted soils improves the conditions for ...
2-vinyl-4h-1,3-dithiin, a bioavailable compound from garlic, inhibits vascular smooth muscle cells proliferation and migration by reducing oxidative stress
(Springer, 2020-05)
Organosulfur compounds (OSCs) of garlic have various health benefits including anti-hypertensive effect. It has been described that volatile OSCs uptake occurs into a moderate extent. Among the bioavailable OSCs present ...
Serotonergic modulation of basolateral amygdala nucleus in the extinction of reward-driven learning: The role of 5-HT bioavailability and 5-HT1A receptor
(Elsevier Science, 2021)
Serotonin (5-HT) neurotransmission has been associated with reward-related behaviour. Moreover, the serotonergic system modulates the basolateral amygdala (BLA), a structure involved in reward encoding, and reward prediction ...