Buscar
Mostrando ítems 41-50 de 425
Vaccination against babesiosis using recombinant GPI-anchored proteins
(Elsevier, 2019-01)
The increase in human babesiosis is of major concern to health authorities. In the USA, most of these cases are due to infections with Babesia microti, whereas in Europe B. divergens is the major cause of clinical disease ...
Immunization with Larrea divaricata Cav. proteins elicits opsonic antibodies against Pseudomonas aeruginosa and induces phagocytic activity of murine macrophages
(Academic Press Ltd - Elsevier Science Ltd, 2018-05)
Pseudomonas aeruginosa is an opportunistic pathogen implicated in nosocomial infections for which no vaccines have been approved. Larrea divaricata Cav. (Jarilla) is a widely spread plant in America and it is used in folk ...
HSP70 family in the renal inflammatory response
(Bentham Science Publishers, 2014-11)
Heat shock proteins (HSP) are a shock induced family of proteins, whose most prominent members are a group of molecules dedicated to maintaining the function of other proteins. Interestingly, after being exposed to heat ...
mPEG-NHS carbonates: Effect of alkyl spacers on the reactivity: Kinetic and mechanistic insights
(John Wiley & Sons Inc, 2018)
Nowadays, the chemical conjugation to mPEG, also known as PEGylation, is a well-recognized technology used to improvethe pharmaceutical properties of the therapeutic proteins. Over the last 20 years, more than 10 PEGylated ...
Dissecting the Immune Stimulation Promoted by CSF-470 Vaccine Plus Adjuvants in Cutaneous Melanoma Patients: Long Term Antitumor Immunity and Short Term Release of Acute Inflammatory Reactants
(Frontiers Research Foundation, 2018-11)
As cutaneous melanoma (CM) currently remains with a bleak prognosis, thorough investigation of new treatment options are of utmost relevance. In the phase II/III randomized clinical trial (CASVAC-0401), the repeated ...
Negative association between 25-hydroxy vitamin d and inflammatory markers in rheumatologic diseasesAsociación negativa entre 25-Hidroxi vitamina D y los marcadores inflamatorios en enfermedades reumatológicas
(Asociación Argentina de Osteología y Metabolismo Mineral, 2021-07)
Objective The main purpose of this study was to evaluate serum 25-hydroxyvitamin D (25OHD) levels and its association with in"ammatory markers in patients with rheumatologic diseases (RD). Methods A cross-sectional study ...
The canonical DHHC motif is not absolutely required for the activity of the yeast S-acyltransferases Swf1 and Pfa4
(American Society for Biochemistry and Molecular Biology, 2015-09)
Protein S-acyltransferases, also known as palmitoyltransferases (PATs), are characterized by the presence of a 50-amino acid domain called the DHHC domain. Within this domain, these four amino acids constitute a highly ...
Presence of estrogen receptor (ER)-like proteins and endogenous ligands for ER in solanaceae
(Elsevier Ireland, 2004-12)
The synthesis of steroid hormones in different plant species and the possibility that these molecules could regulate cell growth, tissue differentiation and germination has been reported. However, the mechanism of action ...
Effect of repetitiveness on the immunogenicity and antigenicity of Trypanosoma cruzi FRA protein
(Academic Press Inc Elsevier Science, 2011-03)
Repetitive proteins (RP) of Trypanosoma cruzi are highly present in the parasite and are strongly recognized by sera from Chagas' disease patients. Flagelar Repetitive Antigen (FRA), which is expressed in all steps of the ...
Photosensitization Reactions of Biomolecules: Definition, Targets and Mechanisms
(Wiley Blackwell Publishing, Inc, 2021-11)
Photosensitization reactions have been demonstrated to be largely responsible for the deleterious biological effects of UV and visible radiation, as well as for the curative actions of photomedicine. A large number of ...