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Pathogenic mechanisms contributing to thrombocytopenia in patients with systemic lupus erythematosus
(Taylor & Francis Ltd, 2021-11)
Systemic lupus erythematosus (SLE) is an autoimmune condition developing thrombocytopenia in about 10?15% of cases, however, mechanisms leading to low platelet count were not deeply investigated in this illness. Here we ...
Galectin-3 deficiency drives lupus-like disease by promoting spontaneous germinal centers formation via IFN-γ
(Nature Publishing Group, 2018-12)
Germinal centers (GC) are important sites for high-affinity and long-lived antibody induction. Tight regulation of GC responses is critical for maintaining self-tolerance. Here, we show that Galectin-3 (Gal-3) is involved ...
Antiphospholipid antibodies impact the protein C (PC) pathway behavior
(Wiley-liss, Div John Wiley & Sons Inc, 2002-10)
Antiphospholipid antibodies may interfere with the PC pathway, displaying a resistance to the activated PC (resistant phenotype). This effect was evaluated by the APCR and the ProCG systems in 36 lupus anticoagulant samples, ...
Perros prehispánicos (Canis lupus familiaris) del Pucará de Tilcara (Provincia de Jujuy, Argentina): Contexto, cronología, morfología y rol socialPrehispanic dogs (Canis lupus familiaris) from Pucará de Tilcara site (Jujuy Province, Argentina): Chronological context, morphology and social role
(Universidad de Tarapacá. Departamento de Antropología, 2021-12)
Se presenta la caracterización de restos inéditos de perros (Canis lupus familiaris) del sitio Pucará de Tilcara (Provincia de Jujuy, Argentina), recuperados en dos contextos arqueológicos (Basural 1 y Acrópolis), que ...
First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)-Pan-American League of Associations of Rheumatology (PANLAR)
(B M J Publishing Group, 2018-11-11)
Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should ...
Forensic analysis of dog (Canis lupus familiaris) mitochondrial DNA sequences: An inter-laboratory study of the GEP-ISFG working group
(Elsevier Ireland, 2009-01)
A voluntary collaborative exercise aiming at the mitochondrial analysis of canine biological samples was carried out in 2006-2008 by the Non-Human Forensic Genetics Commission of the Spanish and Portuguese Working Group ...
Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases
(Elsevier Science, 2015-02)
Dendritic cells (DCs) play a key role in the activation of the immune response against pathogens, as well as in the modulation of peripheral tolerance to self-antigens (Ags). Furthermore, an imbalance in the activating/inhibitory ...
Tuberculosos mucocutánea : presentación de 3 casos y revisión de la literatura
(Universidad Nacional de Cuyo. Facultad de Ciencias Médicas, 2017)
Morphometric analysis of skull shape reveals unprecedented diversity of African Canidae
(Alliance Communications Group Division Allen Press, 2020-05)
We conducted a geometric morphometric analysis to investigate the morphological variation of the golden wolf, Canis lupaster, and to clarify the morphological and taxonomic affinities of different taxa of the genera Canis ...
Morbidity of lupus anticoagulants in children: A single institution experience
(Pergamon-Elsevier Science Ltd, 2004-01)
Introduction: The lupus anticoagulant (LA) and the anticardiolipin antibodies (ACA) are the antiphospholipid antibodies more relevant clinically. Their clinical manifestations are diverse with most patients being asymptomatic ...