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Quantitative structure-activity relationship to elucidate human CYP2A6 inhibition by organosulfur compounds
(IAPC Publishing, 2019-08)
CYP2A6 is a human enzyme responsible for the metabolic elimination of nicotine, and it is also involved in the activation of procarcinogenic nitrosamines, especially those present in tobacco smoke. Several investigations ...
The Change in Psychoactive Substance Consumption in Relation to Psychological Stress During the Covid-19 Pandemic in Uruguay
(Sultan Qaboos University, 2021-05)
Objective: to analyze how the health crisis associated with the Coronavirus disease 2019 (COVID-19) affected psychoactive substance consumption in Uruguay. Method: An online survey was answered by 1916 Uruguayan citizens ...
Evolución de la mortalidad por tumores en las provincias argentinas, 1991-2007Cancer mortality in Argentine provinces, 1991- 2007
(Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Salud Pública y Ambiente, 2012-07)
Objetivo: Analizar la mortalidad por tumores en las provincias argentinas y algunos factores que podrían favorecer su incidencia entre 1991 y 2007, habida cuenta de que el cáncer constituye la segunda causa de muerte en ...
Corporaciones rurales en la provincia de Salta y la integración de la elite provincial en la “Revolución Argentina”
(Universidad Nacional de Quilmes.Centro de Estudios de la Argentina Rural, 2020-01)
El artículo trata sobre la reorganización de las corporaciones rurales de la provincia de Salta en el marco de las nuevas alianzasestablecidas entre las elites argentinas luego del Golpe de Estado de 1955. Dentro de este ...
Ophioviruses CPsV and MiLBVV movement protein is encoded in RNA2 and interacts with the coat protein
(Academic Press Inc Elsevier Science, 2013-07)
Citrus psorosis virus (CPsV) and Mirafiori lettuce big-vein virus (MiLBVV), members of the Ophioviridae family, have segmented negative-sense single-stranded RNA genomes. To date no reports have described how ophioviruses ...
The hamster cheek pouch model for field cancerization studies
(Wiley Blackwell Publishing, Inc, 2015-02)
External carcinogens, such as tobacco and alcohol, induce molecular changes in large areas of oral mucosa, which increase the risk of malignant transformation. This condition, known as ‘field cancerization’, can be detected ...
Isolation and diversity analysis of resistance gene analogues (RGAs) from cultivated and wild strawberries
(Springer Heidelberg, 2004-11)
Degenerate oligonucleotide primers, designed based on conserved regions of Nucleotide Binding Site (NBS) domains from previously cloned plant resistance genes, were used to isolate Resistance Gene Analogues (RGAs) from ...
TMV induces RNA decay pathways to modulate gene silencing and disease symptoms
(Wiley Blackwell Publishing, Inc, 2017-01)
RNA decay pathways comprise a combination of RNA degradation mechanisms that are implicated in gene expression, development and defense responses in eukaryotes. These mechanisms are known as the RNA Quality Control or RQC ...
“Los pasos perdidos”. Proyectos para el Norte Argentino en el Congreso Nacional (1920-1960). Estudio de casos
(Centro de Estudios Históricos Profesor Carlos S. A. Segreti, 2017-08)
Esta investigación histórica analiza las iniciativas y proyectos para la economía agraria del Norte argentino, desde la posguerra, cuando avanza el Estado interventor transformado desde mediados de los 40 en dirigista y ...
Bioinformatic and mutational analysis of ophiovirus movement proteins, belonging to the 30K superfamily
(Academic Press Inc Elsevier Science, 2016-11)
Ophioviridae is a family of segmented, negative-sense, single-stranded RNA plant viruses. We showed that their cell-to-cell movement protein (MP) is an isolated member of the 30K MP superfamily with a unique structural ...