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Protection of cardiac cell-to-cell coupling attenuate myocardial remodeling and proarrhythmia induced by hypertension
(Acad Sciences Czech Republic, 2016-09)
Gap junction connexin channels are important determinants of myocardial conduction and synchronization that is crucial for coordinated heart function. One of the main risk factors for cardiovascular events that results in ...
Von Willebrand factor (VWF) as a risk factor for bleeding and thrombosis
(Maney Publishing, 2012-04)
The von Willebrand factor (VWF) is analysed as a bleeding and thrombotic risk marker. When the VWF level is increased, it predicts a thrombotic phenotype and when VWF level is low in plasma, the phenotype varies to bleeding ...
Calcineurin β protects brain after injury by activating the unfolded protein response
(Academic Press Inc Elsevier Science, 2016-10)
The Ca2 +-dependent phosphatase, calcineurin (CN) is thought to play a detrimental role in damaged neurons; however, its role in astrocytes is unclear. In cultured astrocytes, CNβ expression increased after treatment with ...
Mineralocorticoid Receptors, Neuroinflammation and Hypertensive Encephalopathy
(Springer/Plenum Publishers, 2019-05)
Worldwide, raised blood pressure is estimated to affect 35–40% of the adult population and is a main conditioning factor for cardiovascular diseases and stroke. Animal models of hypertension have provided great advances ...
Identifying pathophysiological bases of disease in COVID-19
(BioMed Central, 2020-09)
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus that can affect lung physiology encompassing a wide spectrum of severities, ranging from asymptomatic and mild symptoms to severe and fatal cases; the latter ...
Placental glycoredox dysregulation associated with disease progression in an animal model of superimposed preeclampsia
(MDPI AG, 2021-04)
Pregnancies carried by women with chronic hypertension are at increased risk of superimposed preeclampsia, but the placental pathways involved in disease progression remain poorly understood. In this study, we used the ...
Non-invasive cardiovascular assessment of pregnancy in healthy female cats
(Elsevier Science, 2021-02)
Introduction: The aim of this study was to evaluate cardiac morphology, indices of systolic and diastolic function, systolic blood pressure (SBP), and uterine artery resistance index (RI) during normal feline pregnancy. ...
Student Developed Knowledge Portfolios from a Soil Fertility Course
(American Society of Agronomy, 2018-12)
<span class="fontstyle0">Students who have completed the Soil Nutrient Relationships course at the University of Nebraska?Lincoln often contact instructors once they have begun full-time work, seeking reminders of specific ...
Impact in the reduction of complications through a personalized follow-up strategy to ensure adherence to antihypertensive therapy
(Institute of Research and Journals, 2019-10)
The lack in continuity of antihypertensive treatment is one of the major common causes of uncontrolled high blood pressure and increased of adverse effects and medical costs associated to this disease. The current study ...
Improved biomechanical metrics of cerebral vasospasm identified via sensitivity analysis of a 1D cerebral circulation model
(Elsevier, 2019-06)
Cerebral vasospasm (CVS) is a life-threatening condition that occurs in a large proportion of those affected by subarachnoid haemorrhage and stroke. CVS manifests itself as the progressive narrowing of intracranial arteries. ...