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Streptococcus pneumoniae galU gene mutation has a direct effect on biofilm growth, adherence and phagocytosis in vitro and pathogenicity in vivo
(Oxford University Press, 2018-10)
Streptococcus pneumoniae, the most common cause of bacterial pneumonia, has developed a wide range of virulence factors to evade the immune system of which the polysaccharide capsule is the most important one. Formation ...
In vitro and in vivo screening of native lactic acid bacteria toward their selection as a probiotic in broiler chickens
(Elsevier, 2015-08)
Among 360 isolates from the gastrointestinal tract (GIT) of broilers, eleven isolates which showed in vitro probiotic properties were identified and selected for further tests. After the in vitro screening, three strains ...
In vivo and in vitro effects of chromium VI on anterior pituitary hormone release and cell viability
(Academic Press Inc Elsevier Science, 2007-12)
Hexavalent chromium (Cr VI) is a highly toxic metal and an environmental pollutant. Different studies indicate that Cr VI exposure adversely affects reproductive functions. This metal has been shown to affect several tissues ...
Speed breeding in pea (Pisum sativum L.), an efficient and simple system to accelerate breeding programs
(Springer, 2020-10)
Time in breeding programs is a key factor. Shortening plant cycles allows to increase the efficiency of the programs. The objective of this work is to compare different rapid generation technologies on commercial varieties ...
A method for in vivo determination of subtilase activity in germinating seeds
(Academic Press Ltd - Elsevier Science Ltd, 2019-01)
Plant proteolytic enzymes belonging to the S8 family of serine proteases are known as subtilases or subtilisin-like proteases. Subtilases compose the largest family of plant serine peptidases and have been associated to a ...
Suicide gene therapy on spontaneous canine melanoma: correlations between in vivo tumors and their derived multicell spheroids in vitro
(Nature Publishing Group, 2010-01)
To validate the use of multicellular spheroids to predict the efficacy of herpes simplex thymidine kinase/ganciclovir (HSVtk/GCV) suicide gene therapy in the respective in vivo tumors, we established and characterized 15 ...
Silicified collagen materials: Modulation of the in vitro and in vivo response
(Elsevier Science, 2019-06)
Collagen derived materials offer distinct advantages over synthetic polymers, considering their natural inherited biocompatibility and mechanical properties. However, because of the extraction procedure, the latter frequently ...
Tolerance to lipopolysaccharide promotes an enhanced neutrophil extracellular traps formation leading to a more efficient bacterial clearance in mice
(Wiley Blackwell Publishing, Inc, 2012-04)
Tolerance to lipopolysaccharide (LPS) constitutes a stress adaptation, in which a primary contact with LPS results in a minimal response when a second exposure with the same stimulus occurs. However, active important defence ...
Effect of sex and genotype of the host on the anthelmintic efficacy of albendazole microcrystals, in the CBi-IGE Trichinella infection murine model
(Cambridge University Press, 2021-11)
Albendazole (ABZ) is an anthelmintic pharmaceutical commonly used in the treatment of nematode infections. It is a Class II drug poorly water-soluble, with very low bioavailability, a feature particularly limiting to treat ...
Early NMDA receptor ablation in interneurons causes an activity-dependent E/I imbalance in vivo in prefrontal cortex pyramidal neurons of a mouse model useful for the study of schizophrenia
(Oxford University Press, 2021-09)
Altered Excitatory/Inhibitory (E/I) balance of cortical synaptic inputs has been proposed as a central pathophysiological factor for psychiatric neurodevelopmental disorders, including schizophrenia (SZ). However, direct ...