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Renal- and calcium-dependent vascular effects of Polybia paulista wasp venom
(Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP), 2011-01-01)
In the present study, the effects of Polybia paulista venom (PPV) on renal and vascular tissues were investigated. Isolated kidneys perfused with PPV (1 and 3 mu g/mL) had increased perfusion pressure, renal vascular ...
Bradykinin-related peptides in the venom of the solitary wasp Cyphononyx fulvognathus
(Elsevier B.V., 2010-02-01)
Bradykinin (BK) and its related peptides are widely distributed in venomous animals, including wasps. in fact, we have previously purified a novel BK-related peptide (BRP) named Cd-146 and the threonine(6)- bradykinin ...
Polybitoxins: A group of phospholipases A2 from the venom of the neotropical social wasp paulistinha (Polybia paulista)
(1998-01-01)
The neotropical wasp Polybia paulista is very aggressive and endemic in south-east Brazil, where it frequently causes stinging accidents. By using gel filtration on Sephadex G-200, followed by ion-exchange chromatography ...
Chemometric analysis of Hymenoptera toxins and defensins: A model for predicting the biological activity of novel peptides from venoms and hemolymph
(2011-09-01)
When searching for prospective novel peptides, it is difficult to determine the biological activity of a peptide based only on its sequence. The trial and error approach is generally laborious, expensive and time consuming ...
A comparative study of protein and enzymatic activity in venoms of some common wasps (Hymenoptera: Vespidae) from São Paulo State
(2004-10-06)
The Hymenoptera Aculeata venoms, with few exceptions, have been poorly studied and characterized. Nevertheless, they have raised increasing interest due to their medical importance, since accidents with these insects are ...
Structure and biological activities of eumenine mastoparan-AF (EMP-AF), a new mast cell degranulating peptide in the venom of the solitary wasp (Anterhynchium flavomarginatum micado)
(Elsevier B.V., 2000-11-01)
A new mast cell degranulating peptide, eumenine mastoparan-AF (EMP-AF), was isolated from the venom of the solitary wasp Anterhynchium flavomarginatum micado, the most common eumenine wasp found in Japan. The structure was ...
Selectivity in the mechanism of action of antimicrobial mastoparan peptide Polybia-MP1
(Springer, 2008-07-01)
Many potent antimicrobial peptides also present hemolytic activity, an undesired collateral effect for the therapeutic application. Unlike other mastoparan peptides, Polybia-MP1 (IDWKKLLDAAKQIL), obtained from the venom ...
Chemical and biological characterization of four new linear cationic α-helical peptides from the venoms of two solitary eumenine wasps
(2011-06-01)
Four novel peptides were isolated from the venoms of the solitary eumenine wasps Eumenes rubrofemoratus and Eumenes fraterculus. Their sequences were determined by MALDI-TOF/TOF (matrix assisted laser desorption/ionization ...
Sequencing wasp venom peptides by endopeptidase digestion and nested collision-induced dissociation/post-source decay methods
(Wiley-Blackwell, 2002-01-01)
A method incorporating nested collision-induced dissociation/post-source decay (CID/PSD) combined with endopeptidase digestion is described as an approach to determine the sequence of N-terminally modified peptides. The ...